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DAY CARE INFECTIONS
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13 million children under 5 years of age use child care services.
National Center for Health Statistics, 2010
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90 percent of families with preschool children use child care services.
National Commission on Children, 2010
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TYPES OF DAY CARE SETTINGS
Small family child-care home 6 children licensing not required Large family child-care home 7-12 children variable licensing requirements Centers 13 children Licensed Facilities for ill children Facilities for children with special needs APHA/AAP Out-of-Home Child Care Guidelines, 1992.
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HIGH RISK PERSONNEL Susceptible to childhood infections
(measles, mumps, chickenpox, etc.) Immunocompromised asplenia cancer transplantation HIV Pregnant women Grossman Ed 8, Infection Control in the Child Care Center, Demos Medical Publisher, 2012
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HIGH RISK CHILDREN Infancy Immunocompromised Chronic lung disease
Risk Factors: Infancy Immunocompromised Chronic lung disease Cardiac disease Physical handicaps Chronic skin disease Grossman, Ed 8, Infection Control in the Child Care Center, Demos Medical Publisher, 2012.
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HIGH RISK CHILDREN FOR SPREADING INFECTION
Children living in impoverished conditions multiple care givers transient “family” or shelter poor sanitary conditions untreated infections in the home Children from developing nations Children with immune deficiencies Children with chronic infections
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DAY CARE FACTORS THAT INCREASE TRANSMISSION OF PATHOGENS
Large numbers of children in close contact Infants and toddlers have no independent personal hygiene are incontinent put everything in their mouths Children are susceptible to most infectious agents Infected children may be contagious before symptomatic Parvovirus B19 Varicella Infected children may be asymptomatic Giardia Hepatitis A
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RESPIRATORY TRANSMISSION
Bacteria Bordetella pertussis Haemophilus influenzae type B Mycobacterium tuberculosis Neisseria meningitidis Streptococcus pneumoniae Viruses Adenovirus Influenza Measles Parainfluenza Parvovirus B19 Respiratory syncytial virus Rhinovirus Rubella Varicella
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FECAL-ORAL TRANSMISSION
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TRANSMISSION BY SKIN OR MUCOUS MEMBRANE CONTACT
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TRANSMISSION BY INOCULATION OR SPLATTERING OF BLOOD
Cytomegalovirus Hepatitis B Hepatitis C Human immunodeficiency virus
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ILLNESSES AND ABSENTEESIM IN DAY CARE CHILDREN (2 YEAR SURVEILLANCE PERIOD)
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ANTIBIOTIC USE IN DAY CARE CHILDREN (2 MONTH SURVEILLANCE PERIOD)
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ENVIRONMENTAL COLIFORM CONTAMINATION (2946 SAMPLES)
Number Contaminated (%) Inanimate objects 307 (15) Toy balls 73 (46) Hands 131 (17) Van et al, JAMA, 1991.
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HEPATITIS A
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HEPATITIS A Child care attendees or employees account for 14% of all cases of Hepatitis A in the United States.
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Small non-enveloped RNA virus
ETIOLOGIC AGENT Small non-enveloped RNA virus
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EPIDEMIOLOGY Source infected human High risk child care centers
large numbers of children longer hours diapered children Mode of spread fecal-oral
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CLINICAL MANIFESTATIONS
Most children are asymptomatic 80% of adults are symptomatic Rash Fatigue Jaundice Anorexia Dark urine Light stools Vomiting
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INCUBATION PERIOD INFECTIOUS PERIOD 15 to 50 days
Among symptomatic persons, infectivity has waned by the time the individual seeks medical care.
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DIAGNOSIS Hepatitis A serology THERAPY Supportive
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PREVENTION Standard precautions Vaccine Immune serum globulin
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CHILD CARE EXCLUSION Infected children can return 10 days after onset of symptoms During an outbreak, return to day care will be governed by the public health department
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RECOMMENDATIONS FOR OTHER CHILDREN
Hepatitis A vaccine Immune serum globulin, if exposed Children should be taught how to minimize risks of transmission by handwashing
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RECOMMENDATIONS FOR PERSONNEL
Hepatitis A vaccine Significant risks of infection in the day care setting
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Pre-attendance Hepatitis A vaccine
PARENTAL ADVICE Pre-attendance Hepatitis A vaccine
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VARICELLA
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BEFORE 1995 INTRODUCTION OF THE VARICELLA VACCINE IN THE UNITED STATES
4 million cases per year 11,000 hospitalizations per year 100 varicella associated deaths Meyer PA et al, J Infect Dis, 2000
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AFTER INTRODUCTION OF VARICELLA VACCINE IN THE UNITED STATES 1995-2000
New Cases: California % Texas % Pennsylvania %
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ETIOLOGIC AGENT DNA virus
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EPIDEMIOLOGY Source infected human: -respiratory tract -infected lesions Mode of spread airborne direct contact
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CLINICAL MANIFESTATIONS
Pruritic vesicular rash Fever Systemic symptoms
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Until lesions are crusted
INCUBATION PERIOD 10 to 21 days INFECTIOUS PERIOD Until lesions are crusted
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Acyclovir for high risk individuals
DIAGNOSIS Clinical Viral culture Serology THERAPY Acyclovir for high risk individuals
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PREVENTION Vaccine Airborne and Contact precautions VZIG in high risk exposed children Post-exposure vaccination of susceptible children and adults
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CHILD CARE EXCLUSION Infected children can return when lesions are crusted (approximately 5 to 7 days)
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RECOMMENDATIONS FOR OTHER CHILDREN
VZIG for high risk exposed children Varicella vaccine RECOMMENDATIONS FOR PERSONNEL Varicella vaccine for susceptible adults
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THEORETIC CONCERNS Increased Varicella in Older Children and Adults who have: Never received the vaccine Have waning immunity Have less booster exposures to VZV later varicella disease herpes zoster
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INFLUENZA
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ETIOLOGIC AGENT Enveloped RNA virus
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EPIDEMIOLOGY Source • infected human Mode of spread
• large droplet aerosol • small droplet aerosol • direct and indirect contact with infected secretions
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INFLUENZAE ATTRIBUTABLE MORBIDITY IN NORMAL CHILDREN LESS THAN 1YEAR OF AGE
Increased Hospitalization Increased Outpatient Visits Increased Antibiotic Use Neuzil KM et al, NEJM, 2000 Izurieta HS et al, NEJM, 2000
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High risk children Chronic lung disease Congenital heart disease Immunocompromised Sickle cell disease Diabetes Chronic renal failure Metabolic disease Under 2 years of age
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CLINICAL MANIFESTATIONS
Fever Headache Myalgias/Arthralgias Chills Pharyngitis Rhinorrhea Cough/Croup/Bronchitis
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INCUBATION PERIOD 1 to 3 days
INFECTIOUS PERIOD Influenza A days prior to 7 days after symptoms Influenza B - 6 days prior to 14 days
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DIAGNOSIS THERAPY Viral Culture Rapid tests (immunofluorescent or
enzyme immunoassay) THERAPY Influenza A -Amantadine -Rimantadine -Zamamivir (inhaled) -Oseltamivir Influenza B -Zamamivir (inhaled)
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PREVENTION Annual influenza vaccine
• high risk children - recommended* • healthy children 6 to 23 months - encouraged* Prophylactic antiviral therapy for high risk children *Recommendations of the ACIP, MMWR, 2002
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CHILD CARE EXCLUSION Until child is able to participate in child care center activities
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RECOMMENDATIONS FOR PERSONNEL
OTHER CHILDREN Avoid aspirin during influenza season Annual influenza vaccine RECOMMENDATIONS FOR PERSONNEL
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MOLLUSCUM CONTAGIOSUM
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ETIOLOGIC AGENT DNA virus
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EPIDEMIOLOGY Source • infected human Mode of spread
• direct skin to skin contact • contaminated formites
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CLINICAL MANIFESTATIONS
Small painless skin lesions notable for a central dimple Lesions are usually on face, trunk and limbs Lesions spontaneously disappear within 6-12 months
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INCUBATION PERIOD 2-24 weeks
INFECTIOUS PERIOD As long as child has visible lesions
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Clinical Biopsy Usually unnecessary Cryotherapy Curettage Laser Cimetidine Topical therapies Acyclovir for high risk individuals DIAGNOSIS THERAPY
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PREVENTION No vaccine available Handwashing
Cover lesions with clothing
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CHILD CARE EXCLUSION None recommended
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PREVENTIVE STRATEGIES
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ENTRANCE REQUIREMENTS FOR CHILDREN
Medical history Immunizations Diphtheria-Pertussis-Tetanus Hemophilus influenza B Hepatitis A Hepatitis B Influenza Mumps Polio Rubella Rubeola Varicella Pneumococcus
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ENTRANCE REQUIREMENTS FOR STAFF
Medical history Immunizations Diphtheria-Tetanus Hepatitis A Hepatitis B Influenza Mumps Polio Rubella Rubeola Varicella (Pertussis)
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EXCLUSION FROM CHILD CARE
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