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Diabetes and Risk of CV Outcomes

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Presentation on theme: "Diabetes and Risk of CV Outcomes"— Presentation transcript:

1 Now or Never: The Cardiologist’s Role in Improving CV Outcomes in Patients With Type 2 Diabetes

2 Diabetes and Risk of CV Outcomes

3

4

5 ACCORD: Baseline HbA1c and Outcomes

6 ORIGIN: Severe Hypoglycemia and Outcome

7 ORIGIN: Median Fasting Plasma Glucose

8

9 Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with DM: SAVOR-TIMI 53

10 SAVOR-TIMI 53: Primary Objective

11 SAVOR-TIMI 53: Changes in Microalbuminuria

12 ADVANCE: Reducing HbA1c Lowers Microvascular Events

13 SAVOR-TIMI 53: Primary End Point

14 Time to Onset of First Primary MACE in Prior Pooled Analysis

15 SAVOR-TIMI 53: Glycemic Indices Over Time

16

17 EXAMINE: Noninferiority Met

18 SAVOR-TIMI 53 and EXAMINE: Effect on CV Risk Factors

19 SAVOR-TIMI 53: Hypoglycemia

20 SAVOR-TIMI 53: Insulin Use

21 SAVOR-TIMI 53: Baseline NT-proBNP and Hospitalization for Heart Failure

22 SAVOR-TIMI 53 and EXAMINE: Conclusions

23 Abbreviations

24 Abbreviations (cont)

25 Abbreviations (cont)

26 References

27 References (cont)


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