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Published byBrooke Bishop Modified over 6 years ago
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Duration of Dual Antiplatelet Therapy Post-ACS: Lessons From Clinical Trials
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Overview
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Case Study
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Acute Intervention
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Current Medications
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Physical Exam/Lab Findings
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Subjective
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Red Flags for Risk of Nonadherence?
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Helpful Tips
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Ubiquity of the Nonadherence Problem
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Addressing Barriers With the Patient as Partner
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DAPT Trial: Stent Thrombosis and MACCE
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PEGASUS: HRs and Rates of the Primary Endpoint
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Relative Risks for All-Cause Mortality in Good vs Poor Adherence to Major CV Medications
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The Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART)
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Major Efficacy and Safety Endpoints in PLATO and SWEDEHEART
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Case Study: 12-Month Visit
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Factors Favoring Longer DAPT
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Calculation of a DAPT Score
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Multivariable Prediction Model and Derivation of the Score
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Effect of Long (12- to 24-Month) vs Short (3- to 6-month) DAPT (ACS Subgroup)
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New Paradigms
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Clinical Decision Making Vision for the Future
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Patient Engagement
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Future of Medication Adherence
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Concluding Remarks
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Abbreviations
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Abbreviations (cont)
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