1. What is a gene?
Homework #1 due 2/7 Bonus #1 due 2/28

2. Chains of DNA can store information:

3. Information flow in cells
CB 5.25
Information flow in cells
Protein

4. The relationship between DNA and genes
a gene - DNA used to produce RNA or protein
promoter
coding region
terminator
non-gene
DNA

5. Only a small percent of DNA codes for proteins
CB 19.14
Only a small percent of DNA codes for proteins

6. DNA Composition: In humans:
Each cell contains ~6 billion nucleotides of DNA.
This DNA is ~2 meters long and 2 nm wide.
~98% does not directly code for amino acids
In a single human cell only about 3-5% of genes are expressed at a time.

7. The length of DNA in each of your cells is longer than you are tall.
human DNA
in each cell
The length of DNA in each of your cells is longer than you are tall.
Width of DNA

8. DNA Composition: In humans:
Each cell contains ~6 billion base pairs of DNA.
This DNA is ~2 meters long and 2 nm wide.
~1.5% directly codes for amino acids
~25% is genes
In a single human cell only about 5-10% of genes are expressed at a time.

9. The relationship between DNA and genes
a gene - DNA used to produce RNA or protein
promoter
coding region
terminator
non-gene
DNA

10. Five Perspectivesof a Gene

11. Genes act as units of heredity…storing and passing on information.
CB 14.14

12. Genes act as units of heredity…
storing and passing on information.

13. Genes are seen as a cause of disease

14. Genes are seen as a cause of disease

15. CB 5.21
Sickle-cell anemia is caused by a single nucleotide change in the hemoglobin gene

16. Genes code for proteins
CB 5.25
Genes code for proteins
Protein

17. Proteins are the “doers” of the cell. They act as: Enzymes
Genes code for proteins…
Proteins are the “doers” of the cell.
They act as:
Enzymes
Structural Support
Transporters
Signals

18. Genes act as switches, controlling development

19. Genes act as switches, controlling development

20. CB 19.14
Genes are replicators
(selfish gene)

21. Viruses infect living cells, take over, and produce more virus.
CB 18.5
Viruses infect living cells, take over, and produce more virus.

22. Bodies are vessels for the transmission of genes

23. Five Perspectives of Genes:
Genes act as units of heredity
Genes are seen as a cause of disease
Genes code for proteins
Genes act as switches, controlling development
Genes are replicators (selfish gene)

24. Transposons

25. Transposons: mobile DNA
CB 19.16
Genes are replicators (selfish gene)
Transposons: mobile DNA

26. Barbara McClintock, discoverer of transposons

27. Transposons are self-moving DNA

28. CB 19.16
Transposons move within genomes via the action of transposase (a protein)

29. Transposons: mobile DNA
CB 19.16
Genes are replicators (selfish gene)
Transposons: mobile DNA

30. CB 19.14
Genes are replicators
(selfish gene)

31. What is a gene? Five Perspectives of Genes:
Genes act as units of heredity
Genes are seen as a cause of disease
Genes code for proteins
Genes act as switches, controlling development
Genes are replicators (selfish gene)
What is a gene?
Homework #1 due 2/7…Bonus #1 due 2/28