1. CHAPTER 8

2. STOCHASTIC Random “all or nothing” linear,nonthreshold
playing the lottery

3. Deterministic Effect AKA nonstochastic or certainty effect
Nonlinear threshold curve
threshold assumed
increases with severity of dose

5. Dose Linear Curves (PG 112 in Sherer, Pg.498-499 Bushong)
Linear, non-threshold
Linear threshold
Nonlinear (Curvilinear, Sigmoid) Threshold curve
Non-linear, non threshold curve
Linear Quadratic Non threshold

8. AGE The age of the biological structure determines sensitivity
Bergonie and Tribondeau
Embryo-fetus-newborn-young child
Decreases in late teens
Stabilizes until old age
increases in old age

9. RECOVERY
Cell can recover if sufficient time is given between irradiation
some cells have greater capacity for repair
Sufficient radiation causes atrophy

10. REVIEW PRINCIPLES OF RADIOBIOLOGY ARE BUILT ON THE FOLLOWING: 1)RANDOM NATURE 2)RADIATION INTERACTS AT CELLULAR LEVEL 3)FACTORS THAT ALTER THESE INTERACTIONS