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Volume 60, Issue 1, Pages (July 2011)

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Presentation on theme: "Volume 60, Issue 1, Pages (July 2011)"— Presentation transcript:

1 Volume 60, Issue 1, Pages 39-44 (July 2011)
Active Surveillance of Small Renal Masses: Progression Patterns of Early Stage Kidney Cancer  Michael A.S. Jewett, Kamal Mattar, Joan Basiuk, Christopher G. Morash, Stephen E. Pautler, D. Robert Siemens, Simon Tanguay, Ricardo A. Rendon, Martin E. Gleave, Darrel E. Drachenberg, Raymond Chow, Hannah Chung, Joseph L. Chin, Neil E. Fleshner, Andrew J. Evans, Brenda L. Gallie, Masoom A. Haider, John R. Kachura, Ghada Kurban, Kimberly Fernandes, Antonio Finelli  European Urology  Volume 60, Issue 1, Pages (July 2011) DOI: /j.eururo Copyright © 2011 European Association of Urology Terms and Conditions

2 Fig. 1 Summary of the numbers of patients and tumors entered in the Renal Cell Carcinoma Consortium of Canada-RC4 study, with their outcomes. AS=active surveillance; SRM=small renal mass. European Urology  , 39-44DOI: ( /j.eururo ) Copyright © 2011 European Association of Urology Terms and Conditions

3 Fig. 2 Summary of those patients who progressed in the Renal Cell Carcinoma Consortium of Canada-RC4 study, with their outcomes. AML=angiomyolipoma; RCC=renal cell carcinoma. European Urology  , 39-44DOI: ( /j.eururo ) Copyright © 2011 European Association of Urology Terms and Conditions

4 Fig. 3 Growth patterns of small renal masses (SRMs) with ≥12 mo of follow-up (151 tumors in 127 patients). The interval observed maximum axial imaged diameter over time for each SRM is subplotted with the overlay of the best fit average growth curves. A mixed-model regression analysis demonstrated an average overall growth rate of 0.13cm/yr (solid line). The average growth rate of those with diagnostic needle core biopsies (46) is represented by the dot dash line for those that were malignant (dot dash line) and the dashed line for those that were benign. European Urology  , 39-44DOI: ( /j.eururo ) Copyright © 2011 European Association of Urology Terms and Conditions

5 Fig. 4 Waterfall plot of the change in maximal axial dimension of each small renal mass from trial entry to last follow-up. European Urology  , 39-44DOI: ( /j.eururo ) Copyright © 2011 European Association of Urology Terms and Conditions


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