1. AMRI - ACCESSIBLE MRI
Team: Raimo Sepponen, Ilkka Laakso, Simo Särkkä, Anouar Belahcen, Matti Linnavuo
Members of Steering Group: Director Jarmo Ruohonen, Philips Medical, Dos Nina Lundbom, HUS Radiology

2. Tool Common Acute and There Is a Need for Semi-Acute Conditions
Brain infarction
Hemorrhage Concussions Inflammation
Sinusitis
Pneumonia
Abscesses
Ascites
Bone fractures Muscle injuries Compartment syndrome Rhabdomyolysis
There Is a Need for
Discriminative
Safe
Accessible
for Diagnosis and Evaluation
Tool
Changes in
Water/Proton
relationships

3. Solution: Point of Care Magnetic Resonance Imaging
Benefits of modern technology:
Discrimination: High sensitivity for free water Safety: Low magnetic field-no missile effects- no patient screening
Low power: Permanent magnet technology
Lightweight: Low field, advanced magnetic construction
Easy to site: e.g. Self-shielded system on a van base_mobile AMRI
Low investment and running costs
Service
Connectivity to cloud based services
Proven diagnostic efficiency:
Premarket Approval (PMA) given by FDA (USA)

4. Brain concussion
Hemorrhage
DR Jan Sääf, Karolinska Institutet
Tech. Sgt. Lachaunda Burley, 436th Medical Support Squadron Diagnostic Imaging flight chief, Dover Air Base :
“If you don’t have [diagnostic imaging], you’re pretty much just guessing what’s wrong with your patient.”

5. AMRI - ACCESSIBLE MRI
Ideal for lightweight and agile mobile MRI units

6. The potential markets Health care – Emergency basic medical care
Customers
Health care – Emergency basic medical care
Military battlefield squadrons
Catastrophe aid – Rapid Response Units
There are 67 nightly operated acute clinics and about 300 day acute clinics in Finland.
In the Nordic countries the number is about 1500.
It may be estimated that within years after the introduction, clinics
have acquired the product which is priced 50 – 70 k€.
The market of Nordic countries will then be M€ within 5 – 7 years.

7. Competition
Customers: Health care, military and catastrophe aid organizations There are not any direct competitors
Emergency CT, MRI and US-services are available especially at higher level of hospitals and emergency clinics
Both CT and High Field MRI have inherent safety risks
Current MRI and CT units are rather demanding to set on a mobile platform
and rather impossible to take in areas of catastrophes or active military sites

8. The current state of the project
Work done:
Specifications have been determined with health care professionals
A preliminary technology and competitor survey is done
A laboratory magnet is available for further development
The electronics modules are designed and major components specified
A network of technology and healthcare professionals is established

9. Project The measures of AMRI are:
The three main goals of the AMRI project are:
Proof of Relevance to be used in the financing negotiations
Proof of Concept and Reference Sites to be used in the marketing of the product
Customer Value assessment for reimbursement application
AMRI main steps are:
Finalizing the novelty and competitor investigations
Study of the business and financing models
Developing a Proof of Relevance
Finalizing the Customer Value assessment
Evaluation work to get the Proof of Concept
The measures of AMRI are:
21 months ( … ), comprising 29 person months
Total budget €, Tekes support of €.

10. Background material and the current state of IPR
The background material belongs to Aalto University
The current state of IPR:
The basic solutions are based on known technology and on expired IPR of various parties. One invention report has been filed
Two invention reports will be filed related to the imaging method and self-shielded installation
Not yet conducted: Preliminary examination of novelty (novelty search), patentability searches and Freedom-to-operate (FTO)

11. TEAM – Yes We Can Prof Raimo Sepponen
Raimo has a unique experience in the Finnish MRI industry. He has been involved in numerous health technology companies and worked with the MRI product development.
Prof Simo Särkkä
Simo studies the processing of multisensor data, especially in the areas of location, health care, machine learning, inverse problem and brain imaging. He also has firm industrial experinece.
Prof Ilkka Laakso
Ilkka is specialized on embedded electronics and measurement techniques. He has worked in Japan in Nagoya Institute of Technology, elaborating especially the use of body models in various studies.
Prof Anouar Belahcen
Anouar works with electromagnetic fields, phenomena and models of magnetic materials and the conversion of energy.
Matti Linnavuo
Matti has a long history with medical electronics research and industry. He has a wide experience in establishing new health technology companies.

12. Raimo Sepponen raimo.sepponen@aalto.fi +358 (0)50 551 2223
Thank you!
Raimo Sepponen
+358 (0)