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Predict the splitting patterns of the protons in a given molecule.

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Presentation on theme: "Predict the splitting patterns of the protons in a given molecule."— Presentation transcript:

1 Predict the splitting patterns of the protons in a given molecule.
Week 12 Analyse a proton NMR spectrum to make predictions about the number of non-equivalent protons and possible structures for the molecule. Predict the splitting patterns of the protons in a given molecule. © Pearson Education Ltd 2009 This document may have been altered from the original

2 Different combinations of spin states for protons in adjacent H atoms
Week 12 Different combinations of spin states for protons in adjacent H atoms © Pearson Education Ltd 2009 This document may have been altered from the original

3 Proton NMR spectrum of methyl propanoate showing splitting patterns
Week 12 Proton NMR spectrum of methyl propanoate showing splitting patterns © Pearson Education Ltd 2009 This document may have been altered from the original 3

4 Week 12 Describe the identification of O–H and N–H protons by proton exchange using D2O. © Pearson Education Ltd 2009 This document may have been altered from the original

5 Water, H2O, and heavy water, D2O
Week 12 Water, H2O, and heavy water, D2O © Pearson Education Ltd 2009 This document may have been altered from the original

6 Proton NMR spectrum of ethanol, C2H5OH: (a) without D2O; (b) with D2O
Week 12 Proton NMR spectrum of ethanol, C2H5OH: (a) without D2O; (b) with D2O © Pearson Education Ltd 2009 This document may have been altered from the original 6

7 Compound with molecular formula C3H7NO2
Week 12 Compound with molecular formula C3H7NO2 © Pearson Education Ltd 2009 This document may have been altered from the original 7

8 Predict the splitting patterns of the protons in a given molecule.
Week 12 Analyse a proton NMR spectrum to make predictions about the number of non-equivalent protons adjacent to a given proton, and possible structures for the molecule. Predict the splitting patterns of the protons in a given molecule. © Pearson Education Ltd 2009 This document may have been altered from the original

9 Proton NMR spectra of ClCH2CH2COOH and CH3CHClCOOH, both in D2O
Week 12 Proton NMR spectra of ClCH2CH2COOH and CH3CHClCOOH, both in D2O © Pearson Education Ltd 2009 This document may have been altered from the original

10 Proton NMR spectra of two esters of C4H8O2
Week 12 Proton NMR spectra of two esters of C4H8O2 © Pearson Education Ltd 2009 This document may have been altered from the original 10

11 Proton NMR spectrum of 2-chloropropane, CH3CHClCH3
Week 12 Proton NMR spectrum of 2-chloropropane, CH3CHClCH3 © Pearson Education Ltd 2009 This document may have been altered from the original 11

12 Proton NMR spectrum of 1,2-dichloroethane, ClCH2CH2Cl
Week 12 Proton NMR spectrum of 1,2-dichloroethane, ClCH2CH2Cl © Pearson Education Ltd 2009 This document may have been altered from the original 12

13 Week 12 Explain that NMR spectroscopy is the same technology as that used in magnetic resonance imaging (MRI). © Pearson Education Ltd 2009 This document may have been altered from the original


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