1. Cytopathology Challenge!
Weekly Cases
September 15th, 2008

2. 1 35 year old female. Breast FNA Apocrine metaplasia
Suspicious for malignancy
Ductal adenocarcinoma
Squamous cell carcinoma
Amoeba 1

3. 2 34 year old female. ThinPrep pap Reactive endocervical cells
Benign endometrial cells
ASCUS
LSIL
HSIL 2

4. 3 Pericardial fluid Benign mesothelial cells Infectious pericarditis
Adenocarcinoma
D. Melanoma
E. Amoeba
Compare malignant cells to a sheet of reactive mesothelial cells in the upper left hand corner. 3

5. 4 Pleural fluid Reactive mesothelial cells Mesothelioma Adenocarcinoma
Squamous cell carcinoma
Small cell carcinoma 4

6. 5 Sputum Negative Amoeba Candida Pneumocystis Candida and Pneumocystis
Did you see the small intracystic trophozoite in the Pneumocystis? 5

7. 6 Urine Negative Low grade TCC High grade TCC
Metastatic prostatic carcinoma
Pinworm 6

8. 7 ThinPrep pap Squamous metaplasia Reactive endocervical cells ASC-US
LSIL
HSIL 7

9. ThinPrep pap
Reactive
Endocervical cells
ASC-US
LSIL
HSIL 8

10. 9 Bronchoalveolar lavage A. Aspergillus B. Mucor C. Candida
D. Fusarium
Scedosporium
Septate hyphae with parallel walls and acute angle branching. 9

11. 10 Liver FNA Negative Amoebic abscess Metastatic adenocarcinoma
Metastatic squamous cell ca
Hepatoma
Malignant hepatocytes with pigment in cytoplasm and intranuclear inclusions. 10