1. Karyotypes

2. Chromosomal Mutations
Not to be confused with point mutations...

3. Translocation

4. Inversions and Deletions

5. What happened here? What cancer is this?
CML where translocation of 22 moves to 9.

6. Mantle cell lymphoma, one altered 11 and 14

8. Meiosis

9. How is meiosis different from mitosis
How is meiosis different from mitosis? Where is the first difference seen? What are the kinetochore microtubules separating?

14. Focus Questions 1.What is the purpose of the first meiotic division?
2.What is the purpose of the second division?
3.In what 2 ways does meiosis alone generate variation necessary for evolution? Provide quantitative explanation using humans who have a 2n number of 46.
4.How does random fertilization generate variation necessary for evolution? Provide a quantitative explanation for this using humans who has a 2n number of 46.
5. Construct a Venn Diagram that compares and contrasts Mitosis and Meiosis
6. How does a trisomy occur?

15. When can non-
disjunction occur?