1. Using the Toolkit to build a CPE policy
Jon Otter & Tracey Galletly
Imperial College Hospitals NHS Trust
@jonotter
Blog:
You can download these slides from:
Using the Toolkit to build a CPE policy

2. Carbapenem-resistant organisms, Europe
EARS-Net

3. Emergence of CPE in the UK
PHE.

4. Detection of new CPE cases at ICHT by month
75% screens, 25% clinical cultures

5. CPE in the UK and US

6. Evidence-free zone

7. Guidelines = Policy

8. Otter et al. Clin Microbiol Infect 2015 2015;21:1057–1066.
CPE Toolbox
Hand hygiene
Cleaning / disinfection
HCW screening
Decol.
Cohorting staff / patients
Note flagging
Education
Env. screening
Contact precautions
Active screening
Antibiotic stewardship
Otter et al. Clin Microbiol Infect ;21:1057–1066.

9. Resources Imperial resources (for sharing!) CPE Policy
CPE patient and staff information
CRO decision tree
Data supporting single CPE admission screen (rather than 3)
Guidelines
PHE CPE Toolkit
HPS CPE Toolkit
ESCMID MDR-GNR Guidelines
UK Working Party MDR-GNR Guidelines
Key publications
Otter et al. Universal hospital admission screening for carbapenemase-producing organisms in a low-prevalence setting. J Antimicrob Chemother in press.
Vella V et al. Isolation demand from CPE screening strategies based on a West London hospital network. J Hosp Infect in press.
Venanzio et al. Screening suspected cases for carbapenemase-producing Enterobacteriaceae, inclusion criteria and demand. J Hosp Infect 2015; 71:
Otter et al. Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries. Clin Microbiol Infect 2015; 21: