1. Sex-linked Genetic Disorders & Autosomal Disorders
Packet #20
Chapter #7

2. Introduction Sex Linked Genetic Disorders Autosomal Genetic Disorders
Disorders caused by malfunctioning genes on the sex chromosome.
Autosomal Genetic Disorders
Disorders caused by malfunctioning genes on an autosome.
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3. Sex-Linked Disorders

4. Hemophilia Hemophilia is an x-linked recessive disorder
Males will show this trait if they have the recessive allele on the X chromosome
Females will show this trait if they have the recessive allele on both X chromosomes
Hemophilia does not allow individuals to have the ability to clot their blood.
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5. Baldness Baldness is an x-linked dominant disorder XBXb
This female will not go bald due to lack of testosterone
XBXB
This individual will start to lose her hair in the future
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6. Autosomal Disorders

7. Huntington Disease Produced by a single dominant allele
No symptoms appear until 30’s and 40’s
Symptoms
Uncontrollable body movements
Degeneration of the nervous system
Usually fatal years after onset of symptoms
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8. Sickle Cell Anemia
Caused by a change in polypeptides found in hemoglobin
Hemoglobin is the protein that carries oxygen in red blood cells
Caused ONLY by co-dominance
The recessive allele causes the change in the polypeptide chain
People that are heterozygous for sickle cell anemia are partially resistant to malaria
Malaria
Caused by the Protist Plasmodium falciparum
Carried by mosquitoes
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9. Sickle Cell Anemia Symptoms Fatigue (feeling tired) Palness
Jaundice (Yellowing of the skin and eyes)
Shortness of breath
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10. Review

11. Review Genetic Disorders Sex Linked Disorders Hemophilia Baldness
Autosomal Disorders
Huntington Disease
Sickle Cell Anemia
Malfunctioning Genes