1. Workshop Overview Obtaining 3D Macromolecular Models
Understanding The Models
Sharing Structure-Function Information
Martz – May 2010

2. Workshop Overview Obtaining 3D Macromolecular Models
Published Empirical (Crystallographic or NMR)
Homology Models
(Theoretical Models Are Grossly Inaccurate)
Understanding The Models
Sharing Structure-Function Information
Martz – May 2010

3. Workshop Overview Obtaining 3D Macromolecular Models
Understanding The Models
FirstGlance in Jmol ( + links to Key Resources)
Proteopedia
Sharing Structure-Function Information
Martz – May 2010

4. Workshop Overview Obtaining 3D Macromolecular Models
Understanding The Models
Sharing Structure-Function Information: Custom Molecular Scenes without Tears
Polyview-3D: publication quality; animations for Powerpoint
Proteopedia: a wiki; rotating molecules; on-line
Martz – May 2010

5. Gal 4 Transcriptional Regulator Protein.
Lysine 18 sits in DNA Major Groove
recognizing CGG. (1d66)
Martz – May 2010 – 1d66

6. Animation Created by Polyview-3D
Gal4:DNA (1d66)
Animation Created by Polyview-3D
(using PyMOL)
Martz – May 2010 – 1d66

7. Mechanosensitive channel Animation by Polyview-3D using PyMOL
(Morph between 2oau & 2vv5)
Morph is also animated in Jmol in Proteopedia