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Published byΕυτροπια Ἰεζάβελ Αντωνοπούλου Modified over 6 years ago
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*Lipoma: -well-circumscribed -homogenous -fatty cut surface -soft
visit for references
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Bland-looking nuclei…small and at the periphery
Mature fatty tissue Bland-looking nuclei…small and at the periphery Large one fat vacuole Visit for references
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Heterogenous cut surface Fixed to the skin and may ulcerate
Large Firm to hard Fleshy Heterogenous cut surface Fixed to the skin and may ulcerate Malignant soft tissue tumor …this example is liposarcoma Visit for references
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This cell is characteristic and it is called: lipoblast
liposarcoma Visit for references
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Intradermal nevus (the most common type of nevus)
Epithelioid benign cells maturation In melanoma: in addition to atypia and invasion, the maturation is lost Lymphocyte-like benign cells Spindle benign cells Visit for references
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The cytoplasm of the cell is filled with this dark brown pigment
Pigmented nevus The cytoplasm of the cell is filled with this dark brown pigment (melanin) Visit for references
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…each cell within lacuna has 1 nucleus
Normal cartilage …small nuclei …each cell within lacuna has 1 nucleus Visit for references
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Chondrosarcoma …notice the atypia
…some cells have more than 1 nucleus in each cytoplasm (binucleation and multinucleation) Visit for references
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Malignant glands with severe architectural
disturbance Lung tissue Adenocarcinoma …May be metastatic or primary …do immunostaining Visit for references
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Stromal reaction (fibrosis) around cancer…= desmoplasia
Metastatic adenocarcinoma in lymph node Visit for references
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Metastatic squamous cell carcinoma in lymph node
Keratin pearl
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Like previous image
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Melanoma …irregular borders …heterogenous with different colors
…underlying tissue destruction …large size Visit for references
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moderate grade squamous dysplasia (changes in lower two thirds)
Most common site of these changes is in transition zone (junction between ecto- and endocervix) Severe squamous dysplasia (full-thickness changes)… = squamous cell carcinoma in situ moderate grade squamous dysplasia (changes in lower two thirds) Low grade squamous dysplasia (changes only in lower third) Robbins and Cotran pathologic basis of disease 9th edition CIN = cervical intraepithelial neoplasia The main cause is HPV Can be detected by cervical (Pap) smear before squamous cell carcinoma occurs Ectocervix: stratified squamous non-keratinized
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