1. Part III Lessons Learned: A Master Class in High-Sensitivity Troponin A Global Perspective

3. Program Goals

4. Prior Programs in Series

5. Case: 47-Year-Old Male Homeless Alcoholic Presentation and Medical History

6. Case Physical Examination Results

7. Case Chest X-Ray, ECG, and Lab Results

8. Case Diagnosis and Repeat hs-cTn Testing

9. ESC Guidelines on the Use of hs-cTn

10. TRAPID-AMI Protocol for Early Rule-Out/Rule-In of AMI

11. Serial hs-cTn Measurement Relative vs Absolute Change

12. hs-cTnT Absolute Δ Change Cutoff for Early Rule-Out of AMI

13. TRAPID-AMI Rule Out AMI With Single Very Low Baseline hs-cTn and No ECG Ischemia

14. TRAPID-AMI Rule-In AMI With Single Very High Baseline hs-cTn

15. Using Lower Risk Score Cutpoints With Contemporary cTn

16. Comparison of Rule-Out Strategies for AMI Using hs-cTn

17. Causes of cTn Elevation

18. APACE Study Design

19. APACE Duration of Outpatient ED Stay

20. APACE Use of Coronary Angiographies

21. APACE Distribution of Coronary Angiography Findings

22. Effect of Elevated cTn Outside of AMI Outcomes in Patients With AHF in ADHERE

23. 3 Keys to Beating Troponinitis

24. ADHERE Patients With AHF Have Elevated cTn

25. Differential Diagnostic Workup

26. PEARL Renal Function and Scaled Troponin

27. Case Revisited

28. Summary of Programs in Series

29. Abbreviations

30. Abbreviations (cont)