1. Chapter 19.6
Gas Transport
Kiana, Heather, Kalli

2. Story Time!

5. Rules of The Game: Goal of The Game:
Houses can only sit with each other
Only four people to a cabin
Occupy the most space in the train and in the city
Goal of The Game:

8. Gas Transport
Blood carries _____ and ______ ______ between the lungs and the body cells
Gases dissolve in the ______ or combine chemically with other atoms or molecules

9. Oxygen Transport
The “oxygen ____” systemic venous blood keeps about ___ of the same oxygen from when it was “oxygen ___”
Keeping the oxygen allows respiratory system to adjust CO2 levels (stabilizes the pH of the internal environment)
Higher __ = easy loading of oxygen
Higher pH is found in the alveoli
Easier for red blood cells to collect oxygen
Lower pH is found in the peripheral tissues
Easier for oxygen to transfer to the tissues for use
SPO2 measures percent of hemoglobin saturated with oxygen
PO2 means partial pressure of oxygen in the blood

11. _________ - protein responsible for transporting oxygen in the blood
Made of heme and globin
Each chain is associated with a ____ group
Heme group surrounds an atom of ____ which binds with an ______ molecule

12. _____________ - the oxygen loaded form of hemoglobin
Hemoglobin is _______ when it is completely loaded with oxygen
Po2
Determines the amount of oxygen that can bind to hemoglobin (____ oxygen molecules can combine to hemoglobin)
The _____ the Po2, the more oxygen binding to hemoglobin
As Po2 decreases, oxyhemoglobin ______ oxygen = oxygen respiration
Especially during ______, increased amounts of oxygen are given off by the oxyhemoglobin due to increasing blood levels of carbon dioxide and temperature

15. Bohr Shift - CO2/Hᐩ are affecting the affinity of Hb for O2
(reduced affinity for O2)
↑ CO2
↑ Hᐩ (↓ pH)
↑ temp
↑ metabolic activity
Bohr Shift - CO2/Hᐩ are affecting the affinity of Hb for O2

18. ________ - a toxic gas created from the incomplete combustion of fuels
Usually produced from __________, ________, and ___________
The toxicity of __________ is created through the binding of hemoglobin
The binding of hemoglobin prevents ________ from delivering to tissues
Carbon monoxide’s polarity causes the CO to stick to the hemoglobin instead of being loosely bound like ___________. This prevents the oxygen from being transported on the hemoglobin.
Carbon Monoxide poisoning is treated through administering ________ at a high partial pressure to increase the amount of oxygen available to the tissues

20. Carbon Dioxide Transport
___________ constantly generates CO2, which diffuses into systemic capillaries
____ is carried into the lungs in three forms:
Dissolving into ______
_______ to hemoglobin
Becoming ___________ ions

21. Ways Carbon Dioxide are Transported
1. As CO2 dissolved in plasma
___ of CO2 is transported by dissolving into the plasma
The amount of CO2 that dissolves into plasma is determined by its ____________

22. Ways Carbon Dioxide are Transported
2. A compound formed by bonding to hemoglobin → _____________
Hemoglobin transport is only ________ of CO2 Transportation
CO2 binds to the ______ at the end of the hemoglobin’s
CO2 does not bind the iron in hemoglobin like oxygen, but rather the amino groups at the ends of the hemoglobin _______ subunits

23. Ways Carbon Dioxide are Transported
3. Bicarbonate ions
____ of CO2 transport
Reacts with _____ to form carbonic acid(H2CO3) with the help of carbonic anhydrase, a catalyst.
The carbonic acid dissociates to release _________ ions and __________ ions
Hydrogen binds to hemoglobin to act as a _______ in order to stabilize the pH
Once the bicarbonate ion moves into the plasma a chloride ion must move into the cell to stabilize the pH this is call the _________

28. Review