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Helena Cuellar and Andre Parrilla

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1 Helena Cuellar and Andre Parrilla
Lysosomes Helena Cuellar and Andre Parrilla

2 Lysosomes = Animal cells

3 Structure Sac/Vesicle single membrane, a phospholipid bilayer
spherical shape contains many enzyme molecules 3D shape protects vulnerable bonds from enzymatic attacks

4 So...where do they come from? ¯\_(ツ)_/¯
This guy Golgi Apparatus (but you already knew that..I hope)

5 Functions Use enzymes to breakdown macromolecules
About 50 different enzymes Hydrolytic enzymes- use water to break down substrates have an acidic interior pH level of about 5 Fuse with old organelles and digest them to destroy and recycle Plasma membrane repair Destroy any foreign material like bacteria or viruses When a cell gets damaged, lysosomes burst and the enzymes eat up their own cells If a lysosome breaks open or leaks its contents, the released enzymes are not very active because the cytosol has a near-neutral pH. However, excessive leak- age from a large number of lysosomes can destroy a cell by self-digestion.

6 Some cells use lysosomes to digest food particles to survive like this Amoeba...

7 Why are lysosomes important?
Allows a cell to renew itself A human liver cell, for example, recycles half of its macromolecules each week. Without it, there would be a build of macromolecules. For example, in Tay-Sachs disease, a lipid-digesting enzyme is missing or inactive, and the brain becomes impaired by an accumulation of lipids in the cells


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