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Volume 129, Issue 2, Pages (August 2005)

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Presentation on theme: "Volume 129, Issue 2, Pages (August 2005)"— Presentation transcript:

1 Volume 129, Issue 2, Pages 494-503 (August 2005)
Survival After Liver Transplantation in Patients With Hepatic Iron Overload: The National Hemochromatosis Transplant Registry  Kris V. Kowdley, David J. Brandhagen, Robert G. Gish, Nathan M. Bass, Jeffrey Weinstein, Michael L. Schilsky, Robert J. Fontana, Timothy McCashland, Scott J. Cotler, Bruce R. Bacon, Emmet B. Keeffe, Fredric Gordon, Nayak Polissar  Gastroenterology  Volume 129, Issue 2, Pages (August 2005) DOI: /j.gastro Copyright © 2005 American Gastroenterological Association Terms and Conditions

2 Figure 1 Kaplan—Meier estimates for survival after liver transplantation in the overall cohort of patients with hepatic iron overload (n = 260). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

3 Figure 2 Kaplan—Meier estimates for survival after liver transplantation among patients based on HFE genotype. C282Y +/+, C282Y homozygous; CPD Het, C282Y/H63D compound heterozygote; Simple het, C282Y/wt or H63D/wt; Wt: wt/wt. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

4 Figure 3 Kaplan—Meier estimates for survival after liver transplantation among patients with HH (defined as C282Y homozygous or C282Y/H63D compound heterozygous [group 1 and group 2]) compared with HFE heterozygotes (C282Y/wt or H63D wt) and patients wild type for HFE [group 3 and group 4]. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

5 Figure 4 (A) Kaplan—Meier estimates for survival among patients with HII >1.9 compared with those with HII ≤1.9. There was no significant difference in survival between the 2 groups. (B) Kaplan—Meier estimates for survival among patients with hepatic iron concentration (HIC) >70 μmol/g dry weight compared with those with HIC ≤70 μmol/g dry weight. There was no significant difference in survival between the 2 groups. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions


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