Presentation is loading. Please wait.

Presentation is loading. Please wait.

Influence of GST Gene Polymorphisms on the Clearance of Intravenous Busulfan in Adult Patients Undergoing Hematopoietic Cell Transplantation  Sung-Doo.

Similar presentations


Presentation on theme: "Influence of GST Gene Polymorphisms on the Clearance of Intravenous Busulfan in Adult Patients Undergoing Hematopoietic Cell Transplantation  Sung-Doo."— Presentation transcript:

1 Influence of GST Gene Polymorphisms on the Clearance of Intravenous Busulfan in Adult Patients Undergoing Hematopoietic Cell Transplantation  Sung-Doo Kim, Je-Hwan Lee, Eun-Hye Hur, Jung-Hee Lee, Dae-Young Kim, Sung-Nam Lim, Yunsuk Choi, Hyeong-Seok Lim, Kyun- Seop Bae, Gyu-Jeong Noh, Sung-Cheol Yun, Sang Beom Han, Kyoo-Hyung Lee  Biology of Blood and Marrow Transplantation  Volume 17, Issue 8, Pages (August 2011) DOI: /j.bbmt Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Comparison of busulfan clearance distribution according to GST genotypes. Horizontal lines indicate the means of each group. (A) GSTA1, (B) GSTM1, (C) GSTT1, and (D) GSTM1/GSTT1-null genotype (ie, the number of GSTM1- and GSTT1-null genotypes). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Clearance of i.v. busulfan according to GST gene polymorphism. Horizontal lines indicate the means of each group. Busulfan clearance was grouped by GSTA1 genotype and GSTM1/GSTT1-null genotype (ie, the number of GSTM1- and GSTT1-null genotypes). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Influence of GST Gene Polymorphisms on the Clearance of Intravenous Busulfan in Adult Patients Undergoing Hematopoietic Cell Transplantation  Sung-Doo."

Similar presentations


Ads by Google