1. Uncommon becoming common…. Case series of fallopian cancers
Uncommon becoming common…. Case series of fallopian cancers *Ragupathy K, Mann J, Dugar N, Iqbal P, Alloub M Doncaster Royal Infirmary
Conclusions
Background
Primary Fallopian tube cancer is very rare with an incidence of only 1 to 2 percent of the gynaecology cancers (1). However, reports are emerging that it might be more common than the historical figure (2).
Method
Data collected between November 2010 and October 2011
Retrospective evaluation of women diagnosed with fallopian cancers, looking at presentation, clinical findings, investigations and the final histology.
Our case series
Literature data
3.6% of all female genital cancers were PFTC 1%
Age range 35 to 78
Median age 55
50% presented with classical signs of adnexal pain and discharge
<15%
50% women were diagnosed as fallopian cancer preoperatively through USS and MRI
0-10% preoperative diagnosis rate because of proximity of tube to ovary and latter being more common
33% had raised CA125 levels
>80%
33% had metastasis to Para aortic lymph nodes
30%
40% were diagnosed with early stage cancer and 60% in advanced stage
45% are in stage I/II and 55% in stage III/IV
PFTC poses a challenge and this case review shows the difficulty in correlating clinic-radiological findings, misleading CA125 levels
A multi-disciplinary approach is advised with low index of suspicion in a postmenopausal woman with adnexal pain and being aware that PFTC is becoming more common than estimated
Returns 1457
Abstracts selected 330
Papers selected 46
Our case series – highest number reported from a single unit in one year
High preoperative radiological diagnosis
Our case series identified PFTC preoperatively in 50% women and we believe MRI done by radiologists with expertise in gynaecology aided by MDT discussion made the difference
REFERENCES
Pectasides D et al, The Oncologist 2006:11:  
Riska A et al, Int J Cancer 2003;104:643–645.
Woolas RP, et al Int J Gynecol Cancer 1997;7:284– 288.
Systematic review on pubmed
* Poster presenter