1. Homework #3 is due 4/11. Bonus #2 is due W 4/4.
Bonus #3 is due F 4/27.
E. coli
Phage virus
Fungus from soil
Ebola

2. The Immune System Specific: Non-specific: B-cells -> antibodies
T-cells
Non-specific:
barriers
CB 43.2

3. Non-Specific Immune System Barriers: Skin-
Dry
Inhospitable
Competition
Secretions (lysozyme)
Hairs and Mucus (protect openings)
Traps particles, swallowed
Stomach acid
kills pathogens
CB 43.2

4. Skin protects us from most pathogens
CB 43.2

5. Non-Specific Immune System Barriers: Skin-
Dry
Inhospitable
Competition
Secretions (lysozyme)
Hairs and Mucus (protect openings)
Traps particles, swallowed
Stomach acid
kills pathogens
CB 43.2

6. esophagus
stomach

7. Non-Specific Immune System Barriers: Skin-
Dry
Inhospitable
Competition
Secretions (lysozyme)
Hairs and Mucus (protect openings)
Traps particles, swallowed
Stomach acid
kills pathogens
CB 43.2

8. The Immune System Specific: Non-specific: B-cells -> antibodies
T-cells
Non-specific:
barriers
CB 43.2

9. The Specific Immune System

10. B-cells and T-cells move through the circulatory system scanning for pathogens

11. B-cells develop in bone marrow T-cells in the thymus
CB 43.10

12. B-cells make and secrete antibodies
CB 43.12

13. Variable region
An Antibody
Constant
region
CB 43.8

14. Antibodies recognize and bind to antigens
CB 43.7

15. B-cells male antibodies that bind to antigens marking them for destruction
Marked for
destruction
by WBC
CB and 19

16. What about damaged or abnormal cells?
Viral infections
Cancer cells
Non-functional cells

17. T-cells recognize and destroy abnormal cells
CB 43.16

18. Immune System Overview
CB 43.14

19. It can take 7-14 days to produce sufficient antibodies to eliminate a pathogen
CB 43.13

20. Memory B-cells make the response to a second exposure more rapid
This is how vaccines work.
Marked for
destruction
by WBC
CB 43.17

21. Vaccines work via memory B-cells that make the response to a second exposure more rapid
CB 43.13

22. The immune system during HIV infection

23. Homework #3 is due 4/11. Bonus #2 is due W 4/4.
Bonus #3 is due F 4/27.
E. coli
Phage virus
Fungus from soil
Ebola