1. Placement of Aeroneb with HFOV
Jim Fink, PhD, RRT, FAARC

2. High Frequency Oscillation Ventilation : In Vitro Setup Infant Ventilation
Setup from podium presentation from ATS, San Diego The vibrating mesh nebulizer is placed in a 15/15mm adapter at the airway
Aerosol Deposition 10.25±6.0%
Demers et al. ATS San Diego, 2005

3. Effect of Nebulizer Position on Aerosol Delivery with HFOV
Cont Gas Flow
Test Lung
Aerosol Deposition 0.47±0.1%
Filter
NEB
HFOV have 20 – 40 LPM going through the vent circuit. Aerosol generated in the circuit is dliluted so very little delivered.
Placement between the gas flow and the patient is much more efficient. With infant ventilator parameter 10% of dose deposited to the end of the endotracheal tube
Cont Gas Flow
Test Lung
Aerosol Deposition 10.25±6.0%
Demers et al. ATS San Diego, 2005

4. A poster from Mark Siobal at SFGH and Georgia State looking at the impact of nebulization with the Aeroneb Solo during HFOV when simulating an adult ARDS patient. Deposition increased as amplitude increased, from 8.7 – 18% deposition. This is similar to the range of deposition achieved with the Solo in adults, peds and infants with conventional ventilation.