1. LOINC-SNOMED Alpha Release March 2016
Lorie Carey

2. Feedback to IHTSDO
Mismatch between the IHTSDO SCTID and the name displayed for 4 maps
17-Hydroxycorticosteroid | should be |17-Ketogenic steroid
Glycogen | should be |Glycogen (starch) synthase
Antigen of Escherichia coli K1 + antigen of Neisseria meningitidis A + B + C + w135 + Y | should be |Antigen of Escherichia coli K1 + antigen of Neisseria meningitidis B
Egg | should be |Egg (yolk and white) specific immunoglobulin E

3. Feedback to IHTSDO Maps with different meanings
LOINC | Saccharides is mapped to Carbohydrate |
In this case, what is LOINC testing for and is it broader or narrower than ‘carbohydrate’?
LOINC has two concepts for Carbohydrate that are also mapped to this SNOMED CT Concept
LOINC | Chenodeoxycholate is mapped to Chenodiol |
LOINC | Complement C4 is mapped to Complement component 4 | but | Complement C3 is mapped to Complement component C3 |

4. Feedback to IHTSDO Maps with different meanings General comments:
Several LOINC components Carnitine.free are mapped to Free L-carnitine | , however SNOMED CT also has |Free carnitine – not sure which one is correct?
LOINC | Latex Ab.IgE is mapped to Hevea brasiliensis specific immunoglobulin E | (Latex is a synthetic compound, whereas Hevea brasiliensis is the rubber tree)
General comments:
It would be helpful to review the parts map
It would be helpful to include the semantic tag in the map

5. Feedback to Regenstrief
In most cases, the LOINC Component and the SNOMED CT Concept were identical
When the two were different, I checked RELMA to see if the SNOMED CT Concept provided in the map was a synonym of the LOINC code
There are a number of times this was not the case, which led me to question the accuracy of the map
There were also times that the LOINC Component was different but both mapped to the same SNOMED CT Concept – these are perhaps duplicate LOINC codes?

6. Synonyms May Be Required
LOINC Component
SNOMED CT Concept
| Lysolecithin acyltransferase
1-Acylglycerophosphocholine acyltransferase |
| Lipoprotein associated phospholipase A2
1-Alkyl-2-acetylglycerophosphocholine esterase |
| 3-Hydroxy-2-Ethylpropionate
2-Ethyl-3-hydroxypropionate |
| Fumarylacetoacetate
4-Fumarylacetoacetic acid |
| 6-Monoacetylmorphine
6-O-monoacetylmorphine |
| Oleate
9 cis-Octadecenoic acid |
| Acid phosphatase.tartrate resistant
Acid phosphatase bone isoenzyme |

7. Synonyms May Be Required
LOINC Component
SNOMED CT Concept
| Swine influenza virus Ab
Antibody to Influenza virus A swine origin |
| Avian reovirus Ab
Avian orthoreovirus antibody |
| Acid beta glucosidase
Beta-glucocerebrosidase |
| Transcortin
Corticotropin binding globulin |
| Terminal deoxyribonucleotidyl transferase
Deoxyribonucleic acid nucleotidylexotransferase |
| TT virus DNA
Deoxyribonucleic acid of Torque teno virus |
| Prostaglandin F2 alpha
Dinoprost |

8. Synonyms May Be Required
LOINC Component
SNOMED CT Concept
| Prostaglandin E2
Dinoprostone |
| Angiotensin converting enzyme
Dipeptidyl carboxypeptidase I |
| Adenosine deaminase binding protein
Dipeptidyl peptidase IV |
| Influenza virus identified
Family Orthomyxoviridae |
| Estradiol.unconjugated and | Estradiol.free
Free estradiol |
| Alpha subunit.free
Free glycoprotein hormone alpha subunit |
| Aldolase
Fructose-bisphosphate aldolase |

9. Synonyms May Be Required
LOINC Component
SNOMED CT Concept
| Fumarase
Fumarate hydratase |
| Acid alpha glucosidase
Glucan 1,4-alpha-glucosidase |
| Reagin Ab
Homocytotropic antibody |

10. Possible Duplicate Codes
LOINC Component
SNOMED CT Concept
| 11-Ketoandrosterone/Creatinine:MRto:24H:Urine:Qn
11-Ketoandrosterone |
| 11-Oxo-Androsterone/Creatinine:MRto:24H:Urine:Qn
| Diphosphoglycerate mutase:CCnc:Pt:RBC:Qn
Bisphosphoglycerate mutase |
| Bisphosphoglycerate mutase:CCnt:Pt:RBC:Qn
| Escherichia coli verotoxic identified:Prid:Pt:Stool:Nom:Organism specific culture
Enterohemorrhagic Escherichia coli |
| Escherichia coli shiga-like identified:Prid:Pt:Stool:Nom:Organism specific culture

11. Possible Duplicate Codes
LOINC Component
SNOMED CT Concept
| HIV 2 gp15 Ab:ACnc:Pt:Ser:Ord:IB
Human immunodeficiency virus 2 protein 15 antibody |
| HIV 2 p15 Ab:ACnc:Pt:Ser:Ord:IB

12. Things I don’t know what to do with?
LOINC Component
SNOMED CT Concept
| Diphtheria sp identified (et al…)
Corynebacterium diphtheriae |
| Diphtheria sp identified
| NADH methemoglobin reductase
Cytochrome-b>5< reductase |
| Cytochrome B5 reductase

13. Questions?

14. Thank you