1. Mitosis

2. What is the importance of cell division?
Reproduction
Growth and development
Tissue renewal

3. Interphase What are the steps? G1, S, and G2 What happens in each?
G1: The cell grows and prepares for duplication
S: the chromosomes duplicate, copying the DNA
G2: the last checkpoint! The cell grows once more and is ready for M phase

4. Some Terms to differentiate
Chromatin
Chromosomes
Sister chromatid
Centromere
When do we use each term? What do they all mean?
Chromatin: DNA and protein coils
Chromosomes: condensed chromatin
Sister chromatid: identical half of a chromosome
What connects the sister chromatids

5. Let’s make a memory cue…because why not
Interphase
Prophase
Prometaphase
Metaphase
Anaphase
Telophase
BE CAREFUL! Cytokinesis is NOT part of the M phase!

6. More terms Centrosome: Group of microtubules Centrioles:
Cylindrical microtubules
Mitotic spindle:
“wires” that pull chromosomes apart
Kinetochore:
where the spindles attach to the chromosome

7. Problems
Sometimes, the checkpoints we talked about do not function correctly. What happens then?
Cancer is a possibility due to rapid and uncontrolled division!
A cell that loses this control undergoes what?
Transformation