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Organic Molecules Mrs. Woodard arnold
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The Universal Solvent – WATER
Day One The Universal Solvent – WATER
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Background Information
Atom- basic unit of matter Proton and neutron- subatomic particles in the nucleus Electron- subatomic particle in charge of bonding on the outside of the nucleus Covalent Bond- Bond in which electrons are shared Ionic Bond- bond in which electrons are donated or received Hydrogen bond- bond caused by differences in charges on a polar covalent molecule
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Why is water So important?
Water is polar which makes it the universal solvent Hydrophilic – polar substances that are easily dissolved in water (i.e. sugar) Hydrophobic – nonpolar substances that are not easily dissolved in water (i.e. oil) Has a neutral pH (acidity vs. basicity) Water forms H+ and OH- ions
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Why is Water So Important?
Water has a high specific heat so it can help normalize temperature changes Specific heat is how much heat is required to change the temp of a substance by 1 degree Water floats when it freezes
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Why is Water So Important?
Cohesion and Adhesion – Water is attracted to water molecules Water is attracted to other substances Allows for molecules to synthesized or hydrolyzed Synthesis – put together Hydrolysis – break apart
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pH scale Compares how acidic substances are Closer to 0 is more acidic
Closer to 14 is more basic
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Buffers Weak acids or bases in a cell that serve as protection against changes in pH Our blood is a buffer solution maintaining a neutral pH of about 7.35 – very close to waters pH
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Most Important Elements to Living Things:
C, H, N, O, P, S Carbon Hydrogen Nitrogen Oxygen Phosphorous Sulfur
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Bell Ringer __________________ is the basic unit of life.
__________________ is a weak acid or base that protects a solution from changes in pH ______________, __________________, _________________, ________________, _________________, and _______________ are the most important elements of life.
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Day Two MACROmolecules
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Organic Compounds Compounds that contain hydrogen and carbon
Macromolecules are LARGE organic compounds
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Carbon Carbon has 4 electrons in outer shell
Carbon can form covalent bonds with as many as 4 other atoms (elements) Usually with C, H, O or N Example: CH4(methane)
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Macromolecules Large organic molecules Also called POLYMERS
Made up of smaller “building blocks” called MONOMERS Examples: 1. Carbohydrates 2. Lipids 3. Proteins 4. Nucleic acids (DNA and RNA)
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How are macromolecules made?
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Dehydration Synthesis
Also called “condensation reaction” Forms polymers by combining monomers by “removing water”.
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How are macromolecules separated or digested?
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Hydrolysis Separates monomers by “adding water”
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Bell Ringer Macromolecules are separated or digested through _____________________. ______________________ ______________________ creates macromolecules. Carbon contains ____________ electrons in its outer shell which allows for it to make ____________ bonds with four other molecules.
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Carbohydrates and Lipids
Day Three Carbohydrates and Lipids
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Recap: 4 types of organic Compounds
Carbohydrate Lipids Proteins Nucleic Acids
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Carbohydrates Most carbohydrates are sugars
Sugar suffix – ose Ex. Glucose, Sucrose, Fructose (high fructose corn syrup) Glucose is the most important organic molecule in the human body!
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Carbohydrates (cont.) Elements in carbohydrates are always:
C:H:O – Carbon:Hydrogen:Oxygen 1:2:1 Ratio Ex. C6H12O6 Monomers – Monosaccharides Ex. Glucose, Fructose, galactose Polymers – Polysaccharides Ex. Chitin, Cellulose
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Polysaccharides Have two uses:
Used as short term energy storage for the human body Are the FIRST source of energy for the body Used as structure Chitin – fungi cell wall, exoskeleton of arthropods Cellulose – plantae cell wall, fiber in our body
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Examples of Carbohydrates
Bread, pasta, rice, potatoes, sugar, fruits, vegetables
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Lipids Elements- C, H, O contains more carbon and hydrogen than oxygen
Monomer Glycerol and 3 Fatty Acids (triglyceride) Examples - fats, waxes, oils, steroids
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Lipids Uses of lipids Second source of stored energy Cell membrane
Insulation Steroid which forms cholesterol Male and female hormones
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Examples of Lipids Butter, Cooking Oil, Lard, Milk Products like Ice Cream, Cheese and Sour Cream
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Fatty Acids Fatty acids are identified as have a carboxyl group in their chain
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3 Types of Lipids Fats Phospholipids Steroids
Saturated Fats - No double bonds so they stack well forming solid lipids Unsaturated Fats - Double bonds do not stack well forming liquids Phospholipids Steroids
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Saturated Fats Saturated fats are bad for the human body because they solidify in the blood vessels Solid saturated fats form plaque that clogs arteries (arteriosclerosis)
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Arteriosclerosis leads to high blood pressure, heart attacks (blockage to heart) and strokes (blockage to brain) Trans Fats - worst kind include extra hydrogens Manufacturers add hydrogens to vegetable oils making them able to stack, increasing their melting point and shelf life
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Bell Ringer ________________ ____________ have no double bonds and stack nicely in the body which can lead to ________________. Carbohydrates have a ratio of ____________ meaning that if C6 then H =___ and O= _______________. The suffix for sugar is always _____________.
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Proteins and Nucleic Acids
Day 4 Proteins and Nucleic Acids
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Proteins Proteins are also called polypeptides
Proteins are amino acids There are 20 amino acids but the human body can only manufacture 11 of them 9 amino acids must be ingested into the body
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Proteins Elements- C, H, O, N, and sometimes S Monomers- Amino Acids
Examples- insulin, human growth hormone, hemoglobin Proteins are the body’s last energy source
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Amino Acid Shapes
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Uses of Proteins Last energy source for the body Building Blocks,
Component of Cell Membrane ENZYMES Antibodies Some hormones Hair & nails
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Proteins in Food Eggs, Nuts, Peanut Butter, Meat, Soy Beans
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Nucleic acids Elements- C, H, O, N, P Monomers- Nucleotides Examples-
DNA-Deoxyribonucleic Acid RNA-Ribonucleic Acid
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Uses of Nucleic Acids Uses- Genetic Material that codes for the production of proteins Nucleotide has three parts: 5 carbon sugar Phosphate Group Nitrogen Base
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Bell Ringer ______________ are the monomers that make up DNA and RNA.
_______________, ___________________, _______________________ are examples of proteins in the BODY. A nucleotide is made up of three parts a _______________ base, a _____________ sugar, and a ______________ group.
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Enzymes and molecule formation
Day 5 Enzymes and molecule formation
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Enzymes Reminder – ENZYMES are PROTEINS
Enzymes lower the energy of activation Energy of Activation – energy required to start a reaction Enzymes are specific – they only fit a certain substrate Lock in key model Catalysts – speed up a chemical reaction without changing in the process
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Lowering the Activation Energy
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Lock and Key Model
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3 Factors Affecting Enzyme Activity
pH Denature - enzyme active site changes shape and can no longer bind with the substrate. Enzyme will denature at the wrong pH which is enzyme specific.
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3 Factors Affecting Enzyme Activity
Temperature Molecules move faster when they are warm, slower when they are cool they bump into the substrate more frequently Too high, will cause the enzyme to denature (change shape) and the substrate can not bind with the active site
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3 Factors Affecting Enzyme Activity
Concentration of Enzyme or Substrate The more enzyme, the greater the chance of the substrate bumping into it. Increases the rate of the reaction until all of the substrate has been used. The more substrate, the greater the chance of the enzyme bumping into it. Increases the rate of the reaction until all the enzymes have substrate in them and the reaction will level off
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Carbohydrates Structure
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Protein Structure
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Lipid/Triglyceride Structure
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