1. Test Slide
Douglas Ong

2. Common medicines that affect cervical mucus douglas ong

3. Common medicines that affect cervical mucus
Too many medicines to cover !
How do they cause mucus changes ?
Can affect local mucus production (increase or decrease)
Can affect systemic hormone balance

4. Classes of Medicines
Hormones

5. Classes of Medicines
Hormones
Cough & Flu

6. Classes of Medicines
Hormones
Cough & Flu
Gastrointestinal

7. Classes of Medicines Hormones Cough & Flu Gastrointestinal
Nervous System
Miscellaneous

8. Hormones DRUG USUALLY PRESCRIBED FOR SITE OF EFFECT TYPE OF EFFECT
Tamoxifen
Breast cancer.
Systemic
Antiestrogen, reduces or suppresses mucus. Menstrual disturbances
Clomiphene
Infertility
Oral Contraceptives
Contraception
Local & systemic
Produce sticky, yellow or white opaque mucus. (Progesterone effect)
Progesterones :
norethisterone,
Depo provera, Implanon, Mirena IUCD
Ovulatory dysfunction
Local & pituitary
Produce sticky, yellow or white opaque mucus.
Estrogens
Produces mucus with fertile signs

9. Cough and Flu Drugs DRUG USUALLY PRESCRIBED FOR SITE OF EFFECT
TYPE OF EFFECT
Ampicillin
Infections
Local
Increase or thin mucus.
Acetylcystine (Flumucil)
Asthma, phlegm
If sufficiently absorbed could increase or thin mucus
Guanifensin (Robitussin)
Cough syrup
Increase or thin mucus
Antihistamines
Coughs, Colds
Decrease amount of mucus, thickening or dryness.

10. Gastro Drugs DRUG USUALLY PRESCRIBED FOR SITE OF EFFECT TYPE OF EFFECT
Atropine, Lomotil,
Imodium
Antispasmodic, stomach pain, diarrhea
Local
Decrease amount of mucus, thickening or dryness.
Propantheline, Buscopan
Antispasmodic
Cimetidine (Tagamet)
Famotidine,
Ranitidine (Zantac)
Stomach ulcers, heartburn or reflux
Local & systemic
Menstrual disturbances
eg non-ovulation
Inhibits histamine, also pituitary gonadatropins (FSH/LH)

11. Nervous System Drugs Antidepressants/ Anti-psychotics :
USUALLY
PRESCRIBED FOR
SITE OF EFFECT
TYPE OF EFFECT
Antidepressants/
Anti-psychotics :
Mellaril, Risperdal,
Valium, Prozac
Depression
Local & systemic
Menstrual disturbances eg non-ovulation
Urecholine (Bethanechol)
Cholinergic agent - urinary retention
Local and systemic
Theoretically could thin secretions.

12. Other less common drugs www.usccb.org/prolife/issues/nfp/drugs.shtml
USUALLY PRESCRIBED FOR
SITE OF EFFECT
TYPE OF EFFECT
Anticancer drugs:
Cancer
Systemic
Suppresses ovulation, induces menopausal (high) levels of FSH, LH.
Dicyclomine
Antispasmodic
Local
Can decrease amount of mucus, can cause thickening or dryness.

13. Miscellaneous Drugs Bromocriptine
Used for treatment of high prolactin (hyperprolactinemia)
Prolactin is a milk hormone
High prolactin inhibits ovulation / fertility
Bromocriptine restores ovulation

14. Prolactin
Produced by pituitary gland in the brain

16. Hyperprolactinemia
Most common type of hormone secreting pituitary tumor
Usually in younger women
Peak incidence 25 – 35 years
Symptoms:
Delayed / absence of menses
Breast milk production
Headaches
Visual changes

17. P o l l e n ? Clinical Situation No. 1
Patient has diarrhea for 2 days. No fever. Seen Dr and told to have upset stomach.
Prescribed lomotil and charcoal
Will her diarrhea affect her charts ?
Which medicines (if any) may affect her charts?
P o l l e n ?

18. T e r e s a ? Clinical Situation No. 2
Patient is trying for pregnancy. Her Dr has prescribed her clomiphene.
Will her charts be affected ?
How will mucus change?
T e r e s a ?

19. Clinical Situation No. 3
Patient is having a flu and cough with high fever.
She has been prescribed
antihistamines,
lozenges,
cough syrup,
panadol,
phlegm medicine (Flumucil)
ampicillin (antibiotic)
Which of these may affect her mucus and in what way ?

20. A n y b o d y ? Clinical Situation No. 3 She has been prescribed
antihistamines,
lozenges,
cough syrup,
panadol,
phlegm medicine (Flumucil)
ampicillin (antibiotic)
Which of these may affect her mucus and in what way ?
A n y b o d y ?

21. Just Remember Classes of Medicines
Hormones
Cough & Flu
Gastrointestinal
Nervous System
Miscellaneous