1. DNA Replication, Repair & Recombination

2. Semi-Conservative Replication
Continuous
Replication
on Leading Strand
Discontinuous
Replication
on Lagging Strand
(Okazaki Fragments)

3. Leading and Lagging Strand DNA Replication
Leading Strand
Lagging Strand

4. DNA Replication

5. DNA Replication

6. DNA Replication

7. DNA Polymerase I

8. DNA Polymerase I Structure

9. DNA Replication Proteins

10. Replication Fork

11. Beta Clamp
DNA
Top View
Side View

12. Chemical Mechanism of Chain Elongation

13. Leading / Lagging Strand Replication

14. DNA Topoisomers

15. Topoisomerase Action

16. Topoisomers/Topoisomerases
L = T+W
L = Linking Number
T = Twists
W = Writhes

17. Polymerase Chain Reaction

18. Polymerase Chain Reaction

19. Polymerase Chain Reaction

20. Polymerase Chain Reaction

21. Polymerase Chain Reaction

22. DNA Proof-reading

23. Prokaryotic vs Eukaryotic DNA Replication
Introduction

24. Chromosomes With Telomeres

25. Linear DNA Replication

26. Telomerase Action

27. Telomerase Action

28. Nucleotide Excision Repair
Bulky DNA Adduct

29. Nucleotide Excision Repair

30. Nucleotide Excision Repair

31. Nucleotide Excision Repair
Thymine Dimers

32. Nucleotide Excision Repair
Partial Strand
Removal
Thymine Dimer
Repair

33. Base Excision Repair
Cytosine Deamination
Cytosine
Uracil

34. Flipping out of
base from helix
Base Excision Repair

35. Uracil-N-Glycosylase Catalysis
Excision of Base
Base Excision Repair
Uracil-N-Glycosylase Catalysis

36. DNA Mismatch Repair
Mismatch

37. DNA Mismatch Repair Unmethylated, recognizable Methylated,
unrecognizable

38. Measuring Mutation
Ames Test

39. DNA Recombination

40. DNA Recombination
Strand Invasion

41. Structure
Introduction

42. DNA Recombination
Holliday Junction

43. Recombination/Repair

44. RecA Recombination Repair in E. coli