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Chapter 35: Antineoplastic Drugs

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1 Chapter 35: Antineoplastic Drugs
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

2 Figure 35.1 Invasion and metastasis by cancer cells
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

3 Figure 35.2 Antineoplastic agents and the cell cycle
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

4 Figure 35.3 Cell kill and chemotherapy
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

5 Figure 35.4 Mechanism of action of the alkylating agents
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

6 Figure 35.5 Structural similarities between antimetabolites and their natural counterparts
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

7 Table 35.1 Classification and Naming of Tumors
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

8 Table 35.2 Agents Associated with an Increased Risk of Cancer
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.


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