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SHANDONG UNIVERSITY Liu Zhiyu
The Cerebellum SHANDONG UNIVERSITY Liu Zhiyu
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Position of Cerebellum
Situated in the posterior cranial fossa Covered superiorly by the tentorium of cerebellum Cerebellum
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Position of Cerebellum
Magnetic resonance images of the cerebellum of a 16-year-old female. Sagittal slice.
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Gross Appearance of Cerebellum
Consists of two cerebellar hemisphere joined by a narrow median vermis
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Gross Appearance of Cerebellum
Superior view Anterior and posterior cerebellar notches Primary fissure Inferior view Tonsil of cerebellum: two elevated masses on inferior surface of hemispheral portion just nearby foramen magnum Posterolateral fissure
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Gross Appearance of Cerebellum
Nodule Uvula of vermis Pyramid of vermis Tuber of vermis
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Lobs of Cerebellum Two deep fissures Three lobs
Primary fissure Posterolateral fissure Three lobs Flocculonodular lobe flocculus and nodule Anterior lobe Posterior lobe Corpus of cerebellar 小脑体
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Structure of the Cerebellum
Gray matter Cerebellar cortex Cerebellar nuclei Dentate nucleus Fastigial nucleus Interposed nuclei Emboliform nucleus Globose nucleus White matter-medulla
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Structure of the Cerebellum
Cerebellar cortex Fastigial nucleus Globose nucleus Dentate nucleus Emboliform nucleus medullary center
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Three Functional Divisions
Vestibulocerebellum Archicerebellum Flocculonodular lobe Spinocerebellum Paleocerebellum Anterior lobe and uvula and pyramid of vermis Cerebrocerebellum Neocerebellum Posterior lobe except uvula and pyramid of vermis
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White matter of cerebellum
Three peduncles Inferior cerebellar peduncle -connect with medulla and with spinal cord, contain both afferent and efferent fibers Middle cerebellar peduncle -connect with pons, contain afferent fibers Superior cerebellar peduncle -connect with midbrain, contain mostly efferent fibers
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Connections and Function of Cerebellum
Archicerebellum (Vestibulocerebellum) Connections Afferents: receive input from vestibular nuclei and primary vestibular Efferents: projects to the vestibular nucleus → vestibulospinal tract and medial longitudinal fasciculus → motor neurons of anterior horn Function: involved in eye movements and maintain balance
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Connections and Function of Cerebellum
Paleocerebellum (Spinocerebellum) Connnection Afferents: receive somatic sensory information via spinocerebellar tracts Efferents fibers: projects to the fastigial and interposed nuclei → vestibular nuclei, reticular formation and red nucleus → vestibulospinal tract, reticulospinal tract and rubrospinal tract → motor neurons of anterior horn Function: control of muscle tone
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Connections and Function of Cerebellum
Neocerebellum (Cerebrocerebellum) Connection Afferents: receives input from the cerebral cortex via a relay in pontine nuclei Efferents: projects to dentate nucleus → dorsal thalamus and red nucleus→ primary motor cortex → corticospinal tract → motor neurons of anterior horn Function: coordinator of precise movements
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fMRI (functional magnetic resonance imaging) of a volunteer executing repetitive finger movements of the right hand. The arm/trunk areal activity is attributable to a stabilization function.
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