1. Mitosis & The Cell Cycle
SPI.1.6 Determine the relationship between cell growth and cell reproduction.

2. Why Cells go through Mitosis. . .
Multicellular
Unicellular
Growth
Repair
Reproduction
Binary fission

3. metaphase THE anaphase telophase prophase CELL CYCLE ~ 1 The Life
M I T O S I S
metaphase
THE
CELL
CYCLE ~
anaphase
prophase
telophase 1 G2
(Gap 2)
The Life
Cycle of
The Cell
cytokinesis 2
3 Parts in the Cell Cycle
Interphase*
Mitosis
Cytokinesis G1
(Gap 1)
S-Phase
(DNA Self-
Replication)

4. Mitosis Purpose: Form TWO Nuclei Goal: Same kind of DNA
Same number of DNA
Amoeba Sisters video link on mitosis

6. Karyotype

7. DNA Chromosome Condensed (wrapped up) Chromatin Thin thread like
Chromatid
2 chromosomes held together by a centromere

8. INTERPHASE: Gap 1 MITOSIS Gap 2 S-phase Normal cell functions
INTERPHASE is not a stage of mitosis !
Gap 2
S-phase
Prep for Mitosis
Synthesis of DNA
Biological Science, a Molecular Approach.
BSCS Blue Version. Heath and Company, 1996.

9. Interphase Nucleolus visible Nuclear membrane present DNA- chromatin
Centrioles
Nuclear membrane present
DNA- chromatin

10. Prophase Spindle forms Centrioles migrate to poles of the cell
nuclear membrane
disappears
chromosomes
condense
nucleolus
disappears

11. Metaphase Chromatids line This organizes the DNA up in the MIDDLE
____________
Chromatids line
up in the MIDDLE
of the cell
This organizes
the DNA
Middle of the
cell is called
the equator..

12. Anaphase Chromatids move AWAY… Chromatids separate & move towards
__________
Chromatids move
AWAY…
Chromatids separate
& move towards
the poles

13. Nuclear membrane reforms
Telophase
Chromosome unwind
into chromatin
Spindle fibers
disappear
Nuclear membrane reforms
Nucleolus
reappears

14. Which Stage? 1 5 2 3 6 4 7

15. Cytokinesis
The division of the cytoplasm and the rest of the cell besides the nucleus.

16. Cytokinesis Plant Animal Cell Plate Inside  Out Cleavage Furrow
Outside  In

18. Cancer Uncontrolled cell growth
Cells do not respond to regulation signals
Cause tumors
Defect in tumor
suppressor gene
Video on Cancer on Cancer heading