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HIV: Clinical manifestations

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Presentation on theme: "HIV: Clinical manifestations"— Presentation transcript:

1 HIV: Clinical manifestations
Edina H. Moylett, MD, William T. Shearer, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 110, Issue 1, Pages 3-16 (July 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Graphic representation of the global distribution of HIV and AIDS. Figure adapted from the Joint United Nations Programme on HIV-AIDS. (UNAIDS. Global HIV/AIDS and STD Surveillance. Available at Journal of Allergy and Clinical Immunology  , 3-16DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 Proposed spectrum of clinical and biochemical abnormalities in HIV-associated fat-redistribution syndromes. PI exposure results in hyperlipidemia with primary lipohypertrophy. NRTI exposure results in significant mitochondrial toxicity and resultant lipodystrophy. Journal of Allergy and Clinical Immunology  , 3-16DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

4 Fig. 3 Oral hairy leukoplakia in a young immigrant child with previously undiagnosed HIV infection. This is an unusual clinical manifestation in the pediatric population. Journal of Allergy and Clinical Immunology  , 3-16DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

5 Fig. 4 Severe Candida species esophagitis in an adolescent patient with advanced HIV-AIDS receiving HAART (poor compliance). HSV was also isolated from a biopsy sample on viral culture. Journal of Allergy and Clinical Immunology  , 3-16DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions


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