1. Efficacy of Cangrelor vs. Clopidogrel
Odds Ratio
[95% CI]
P value
Death/MI Universal Definition/IDR
203 (3.1)
244 (3.8)
0.82 [0.68–0.99]
0.0422
Death
14 (0.2)
23 (0.4)
0.60 [0.31–1.18]
0.138
MI Universal Definition
172 (2.6)
194 (3)
0.88 [0.71–1.08]
0.2222
IDR
32 (0.5)
47 (0.7)
0.68 [0.43–1.06]
0.0878
Stent thrombosis (ST)
12 (0.2)
27(0.4)
0.44 [0.22–0.87]
0.0184
Death/MI Universal Definition/ST
190 (2.9)
228 (3.5)
0.82 [0.68–1.00]
0.0517
MI original definition
455 (7)
447 (6.9)
1.01 [0.88–1.16]
0.8510

2. Efficacy of Cangrelor in Thienopyridine Naïve Patients
Clopidogrel (%)
(n=5,067)
Odds Ratio
(95% CI)
P value
Death/MI/IDR
153 (3%)
131 (3.6%)
0.84 [0.67–1.04]
0.106
Death/Q MI/IDR
38 (0.7%)
65 (1.3%)
0.58 [0.39–0.86)
0.0075
MI Universal Definition
9 (0.2%)
20 (0.4%)
0.45 [0.20–0.98]
0.0446
IDR
11 (0.2%)
24 (0.5%)
0.45 [0.22–0.93]