1. How did scientists finally discover the causes of disease?
Early stages

2. By the end of the lesson you ...
must be able to describe how people linked germs and disease.
should be able to name factors which helped each step and give examples.
Could explain how factors enabled these discoveries and explain links between them.

3. Louis Pasteur, Scientist who published
Germ Theory in 1861
1826 Improved microscope by Joseph Jackson Lister.
Brewery work
1875 Doctor Robert Koch began to investigate whether specific bacteria caused specific diseases
Disproved theory of spontaneous generation

4. Pages
On your mind map add details of the work and discoveries of Pasteur and Robert Koch. Ensure you include any further dates.
In a different colour pen write in where the following factors helped their work.
Chance
Technology
Industry
Science

5. So bad, it’s good?

6. Page 25
Complete activities.

7. Germ theory – remember it!
1861

8. Scientists now knew that germs cause disease
There were two ways this could be developed to benefit health.
What were they?
Prevention
Cure

9. The Development of Germ Theory
For centuries people had made a common-sense link between and In the late 1600s a Dutch clockmaker called made some of the earliest . With these he saw which he called Technical advances as part of the
improved the quality of glass, and a scientist called
developed a better which showed clearer and more detailed images.
One theory about these organisms was that decaying matter
them. This was called In
an alternative theory was published by . He believed that decay was caused by in the .

10. Worksheet 53 What the step involved Why this step was so important
The important factors which helped scientists make the step.
Discovering micro-organisms
Improved microscopes
Pasteur’s germ theory
Germ theory vs. spontaneous generation (and it wins!)
Linking micro-organisms to disease.
Proving the link between bacteria and human disease.

11. Why this step was so important
What the step involved
Why this step was so important
The important factors which helped scientists make the step.
Discovering micro-organisms
Improved technology
Improved microscopes
Science
Pasteur’s germ theory
Links with industry.
Science/ Individual genius
Germ theory vs. spontaneous generation (and it wins!)
Competition
Scientific method
Linking micro-organisms to disease.
Individual genius.
Links with industry
Proving the link between bacteria and human disease.
Communication.
Scientific method.

12. Why this step was so important
What the step involved
Why this step was so important
The important factors which helped scientists make the step.
Discovering micro-organisms
Knew they existed (but not what they were).
Improved technology
Improved microscopes
Enabled closer examination of micro-organisms.
Science
Pasteur’s germ theory
Finds that micro-organisms can have an effect on substances.
Links with industry.
Science/ Individual genius
Germ theory vs. spontaneous generation (and it wins!)
Moved away from a misleading idea.
Competition
Scientific method
Linking micro-organisms to disease.
Suggests the connection for the first time.
Individual genius.
Links with industry
Proving the link between bacteria and human disease.
One of main causes of disease has been identified.
Communication.
Scientific method.