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Punnett Squares
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DOMINANT/RECESSIVE Dominant allele is represented by a capital letter. (usually the first letter of the trait) Recessive allele is represented by the SAME letter except in lower-case. EX: (Trait: height) Tall = T Short = t; not s for short
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Misconceptions About Dominant Alleles
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The genetic makeup (set of 2 alleles) of an organism is its genotype
Genotype & Phenotype The genetic makeup (set of 2 alleles) of an organism is its genotype The physical appearance of an organism is its phenotype
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Genotype vs. Phenotype
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Talk to a Partner: Determine the genotype and phenotype of each flower
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HOMOZYGOUS & HETEROZYGOUS
When both alleles in the pair are the same, the organism is homozygous (purebred) EX: TT or tt When both alleles in the pair are different, the organism is heterozygous (hybrid or carrier) Ex: Tt
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Which chromosome set is heterozygous?
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Punnett Squares (PSq) Developed in 1905 by Reginald Punnett.
Used to predict & compare possible genetic variations resulting from a cross Probabilities, not exact results
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PROBABILITY ____________________ is the liklihood that a particular event will occur It can be written as a: Fraction ____ Percent ____ Ratio ____ (dominant : recessive) 1/4 25% 1:3
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Symbols used in PSq Original parents P1 generation
Offspring of the parent plants F1 generation Offspring of the F1 generation F2 generation
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Explaining Mendel’s Results using Punnett Squares
Creating Pure breeding P generation PP X PP pp X pp
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Explaining Mendel’s Results using Punnett Squares
Creating F1 generation: PP X pp
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Explaining Mendel’s Results using Punnett Squares
Creating F2 generation: Pp X Pp
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Practice Problem: Monohybrid Crosses: Working w/ PS #1
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Now try problems on: Punnett Squares Practice: Monohybrid Crosses
STOP !!
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Non-Mendelian Genetics
Patterns that don’t follow Mendel’s Rules
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1) Incomplete Dominance
Two different alleles BLEND to form a new phenotype Ex: Colors in flowers, red + whitepink
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2) Codominance Two different alleles of the same trait are completely and fully expressed EX: Red flower & white flower produces a red and white striped flower
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Examples
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2. Codominance & Multiple Alleles
Classic Ex: Human blood types - A, B, AB, O Alleles: IA, IB, i IA & IB are codominant i - recessive (ii = type O blood)
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Genotype IA IA or Iai IB IB or Ibi IA IB ii
Phenotype
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IA IA or IAi A IB IB or IBi B IA IB A and B AB ii none O
Genotypes Surface Proteins Phenotypes IA IA or IAi A IB IB or IBi B IA IB A and B AB ii none O
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A and AB see A as “like me” as Different!
DONOR BLOOD A and AB see A as “like me” B and O see A as Different! IMMUNE SYSTEM ATTACKS! Body images modified from:
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B and AB see B as “like me” as Different!
DONOR BLOOD B and AB see B as “like me” A and O see B as Different! IMMUNE SYSTEM ATTACKS! Body images modified from:
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O ____ can donate to EVERY BLOOD TYPE = _____________________
DONOR BLOOD O ____ can donate to EVERY BLOOD TYPE = _____________________ Nothing on surface to recognize as “NOT SELF” UNIVERSAL DONOR YOU DON’T HAVE ANYTHING I DON’T HAVE! Body images modified from:
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AB can only GIVE to AB BUT . . .
______ can RECEIVE FROM EVERY BLOOD TYPE = ________________________ UNIVERSAL RECIPIENT Body image modified from:
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Comparison Codominance Incomplete dominance
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Practice Problem: Incomplete Dominance Working w/ PS #3,4 & 6
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Now try problems on: Punnett Squares Practice: Incomplete/Codominant
STOP !!
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Non-Mendelian Genetics
Patterns that don’t follow the rules Incomplete Dominance Codominance
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3) Sex-linked traits Traits carried on the sex chromosomes (mostly the x chromosome)
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Ex. Colorblindness, hemophilia
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4) Polygenic traits Trait produced from many alleles on more than one chromosome Ex. Hair color, skin color, eye color, height
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The more genes that contribute to the trait, the more complicated the pattern of expression
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Practice Problem: Incomplete Dominance Working w/ PS #2, 5
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Now try problems on: Punnett Squares Practice: Sex-Linked STOP !!
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