1. The Status and Future of Integrative and Organ Systems Sciences October 20 – 21, 2002 Bethesda, MD
Sponsored by: APS and ASPET
Co-sponsors: Burroughs Wellcome Fund
Merck Research Laboratories

2. Definitions
Reductionist approaches are aimed at identifying molecular and cellular events, studied in purified form or in isolated systems and including genomics, proteomics, biochemistry and cell biology
Integrative and Organ Systems approaches are aimed at understanding how intact biological systems function at the level of whole animals, organs and organ systems (but not in the clinic).

3. Life Sciences Research Office (LSRO)
Michael Falk
Executive Director

4. Mission
To benefit society by evaluating biological information and scientific opinion for the public and private sectors

5. Steering Committee James R. Bloedel Joseph R. Haywood
D. Euan MacIntyre
Peter C. Preusch
James H. Woods
Edward J. Zambraski

6. HGS Annual Reports
Founded in 1992 – leader in the discovery of human and microbial genes
“success in turning our leadership in gene discovery into leadership in the creation of proprietary pharmaceutical products”
“year of change for our company, as we began to implement clinical development of our own drugs”
“significant progress in its ongoing transition to a fully integrated biopharmaceutical company that discovers, develops, manufactures and markets”
“genomics” found only once