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Dedicated mTEC Progenitors Stay True, Even into Adulthood

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Presentation on theme: "Dedicated mTEC Progenitors Stay True, Even into Adulthood"— Presentation transcript:

1 Dedicated mTEC Progenitors Stay True, Even into Adulthood
Korosh Kianizad, Juan Carlos Zúñiga-Pflücker  Immunity  Volume 41, Issue 5, Pages (November 2014) DOI: /j.immuni Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Figure 1 Schematic View of Progenitor-Progeny Relationships of Different TEC Subtypes The adult thymus contains a self-renewing pool of stem cells, which can give rise to both cTECs and mTECs. Additionally, a pool of self-renewing Cld3,4hiSSEA-1+ mTECSCs can give rise exclusively to mTECs. However, it is unknown whether these mTECSCs arise from the common adult TEC stem cell or whether they are embryonically derived. Additionally, the immediate progeny of the common TEC stem cell remains to be definitely identified. Immunity  , DOI: ( /j.immuni ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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