1. Pathological Conditions
and
Infectious Diseases

2. Buffet

3. Barriers
Why?

4. Barriers
Keeping the Inside In
Keeping the Outside
Out

5. Carcinomas
80 – 90% of all cancers
Are from?

6. Carcinomas
80 – 90% of all cancers
Epithelial Cells

7. Epithelia

8. Lymphoid System

9. Liver

10. Urinary system

11. On all content: Date

12. On all content: Block

13. Generic: Where

14. Generic: What

15. Generic: How

16. Elaborate
Anatomy
Physiology
Pathology
Experiences?

17. Goals: Lymphoid Tissues
Identify, describe and distinguish:
lymph nodules, tonsils, lymph nodes, thymus and spleen.
Explain flow of lymph & blood through the lymph node and spleen respectively.
Explain how the structure of the lymphoid organs facilitate their function.
Explain age related changes in the thymus.
Describe distribution, organisation and significance of MALT.
Differentiate between B- and T-sell regions.

18. Tasks: Lymphoid Tissues
Complete table comparing lymphoid tissues and organs.
Compare low magnification view of the lymphoid tissues and organs with diagrams of each.
Make own annotated diagram of each structure.
Complete the drawings for each slide in the practical workbook.
Connect the histological structures with the relevant macroscopic anatomy, physiology and pathology.

19. Lymphoid Tissues Capsule? Cortex-Medulla? Germinal Centers?
Tissue/Organ
Capsule?
Cortex-Medulla?
Germinal Centers?
Lobulation?
Cells?
Notes
Lymph Nodule
Tonsils
Lymph Node
Thymus
Spleen

20. Goals: Liver Describe role of the liver in the digestive process.
Describe structure of the liver lobule, its component cells & how this structure is related to the flow of blood and bile.
Describe relationship between blood flow through the liver & pathologies.
Describe the origin & destination of the various secretory products of the liver.

21. Tasks: Liver
Make annotated diagrams of the three alternative views of liver structure.
Explain the relevance of each structural unit of the liver.
Using the relevant structural unit, explain liver damage seen in the liver.
Compare and correlate the annotated diagrams with the histological view of the liver.
Complete the drawings for each slide in the practical workbook.

22. Goals: Urinary System
Distinguish the components of the renal cortex and medulla.
Identify each component of the nephron and the function of each.
Identify and describe the proximal tubule, distal tubule, and collecting duct.
Identify and describe the components of the juxtaglomerular apparatus.
Name and identify the histological characteristics of the ureter, bladder and urethra.
Contrast and compare the epithelia present in each of the structures and how this aligns with the function of each structure.

23. Tasks: Urinary System Describe the flow of blood through the kidney.
Describe the production and flow of urine through the kidney up to and including the urethra.
Make an annotated drawing of the macroscopic view of the kidney.
Make an annotated diagram of a nephron, including the juxtaglomerular apparatus. Indicate the flow of blood and water in each part, and how solutes are filtered, secreted and reabsorbed.
Complete the drawings for each slide in the practical workbook.

24. Lymphoid system List: Components of lymphoid system
Purpose of each – keep in mind barrier concept
Characteristic of each component
Common to all components
Blood/Lymph flow through each component

25. Lymphoid system Liver Kidney Structures Substances Paths Slides
List all substances moving through the structure.
Paths
List the path these substances take through the structure.
Slides
Correlate with the microscopic structure.

26. Traumatic events in the liver
Illustrate the damaged area of Liver acinus
Visible histologically
Caused By Various Agents / Diseases
Describe the mechanism
Identify and explain the area
Indicate zones of damage
Correlate with slide

27. Indicate areas sensitive to ingested toxic substances.
Liver acinus
Indicate areas sensitive to ingested toxic substances.

28. Indicate areas sensitive to ischemia.
Liver acinus
Indicate areas sensitive to ischemia.

29. Indicate areas least sensitive to ischemia.
Liver acinus
Indicate areas least sensitive to ischemia.

30. Indicate areas susceptible to viral hepatitis.
Liver acinus
Indicate areas susceptible to viral hepatitis.

31. Indicate areas susceptible to paracetamol.
Liver acinus
Indicate areas susceptible to paracetamol.

32. In which area does haemosiderin accumulate?
Liver acinus
In which area does haemosiderin accumulate?

33. In which area will Flavivirus cause necrosis?
Liver acinus
In which area will Flavivirus cause necrosis?

34. Kidney Make a line diagram Label the colour slides.
Annotate the two diagrams
Complete the diagram:
Events in each part of the nephron
Stimulate / Inhibit

35. Kidney

36. Slides: Lymphatic system
Slide 22: Lingual tonsil 10
Slide 62: Thymus 15
Slide 63: Palatine Tonsils 16
Slide 64: Spleen 17
Slide 65: Thoracic Duct 18
Slide 66: Lymph Node 19
Slide 75: Thoracic Duct 27

37. Slides: Liver Slide 46: Liver 12 Slide 48: Liver – reticular fibers 13

38. Slides: Urinary system
Slide 28: Kidney 11
Slide 76: Kidney – simple cuboidal epithelium 28
Slide 76: Kidney 29
Slide 78: Ureter: urothelium (transitional) 30
Slide 78: Ureter 31
Slide 79: Bladder 32

39. Reflection on session Evaluation and Suggestions re Venue
What happened in the session today?
What went well in today’s session?
What can be done to improve the session?
Evaluation and Suggestions re Venue
Consider the contribution of
Yourself
Your Team
Your Facilitator

40. All other material, for STUDY!
To exit
Show completed tasks
Hand in reflection on session
ONLY REFLECTION
All other material, for STUDY!

41. Kidneys Protein Exercise High Protein Diet
Safe? Not safe?
Mechanisms?

42. After session @ home Complete Work book ClickUP Open book revision
CrossWords
FlashCards