1. What does this protein make up or do?
Chapter 5: Chromosome 5
Name of Protein
DNA Sequence
Solute Carrier Family
Chromosome 5
49755
Name of Gene
SLC22A4
transcription
Amino acid sequence
mRNA
551 aa
translation
Cytoplasm
A Cell
Nucleus
What does this protein make up or do?
Makes up Chromosome 5
Condition/Disease
Crohn’s Disease

2. Description of Glaucoma
Symptoms and characteristics
Abdominal pain. Often cramping and intermittent. The abdomen may be sore when touched. Abdominal pain may feel like a dull, constant ache depending on the location of inflammation
Diarrhea. Some people have diarrhea many times a day and need to wake up at night to go to the bathroom
Unintended weight loss. Ongoing symptoms, such as vomiting or diarrhea, can lead to substantial weight loss
Normal Vision
As viewed by a person with glaucoma
Pictures used with permission from URL:

3. Description of Crohn’s Disease(cont.)
Who is affected?
Age. Crohn's disease can occur at any age, but you're likely to develop the condition when you're young. Most people who develop Crohn's disease are diagnosed before they're 30 years old
Ethnicity. Although Crohn's disease can affect any ethnic group, whites and people of Eastern European (Ashkenazi) Jewish descent have the highest risk.
Cigarette smoking. Cigarette smoking is the most important controllable risk factor for developing Crohn's disease. Smoking also leads to more severe disease and a greater risk of having surgery. If you smoke, it's important to stop.
Family history. You're at higher risk if you have a close relative, such as a parent, sibling or child, with the disease. As many as 1 in 5 people with Crohn's disease has a family member with the disease.
Outlook or quality of life:
To compare health-related quality of life in Crohn's disease patients with that in other patients and healthy controls, and between medically and surgically treated Crohn's disease patients, and to correlate health-related quality of life with Crohn's disease activity.

4. References
NCBI. Genes and Disease: Crohn’s Disease[online] [cited 2015 March 3]. Available at
URL:
NCBI. Entrez [online] [cited 2004 July 14]. Available at URL:
Researched By: KS