1. Case presented by Dr Moriarty
83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies
2010: Increased bleeding and abdominal pressure
PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes
Biopsy = adenocarcinoma of the rectum
Consultation to discuss tx for locally advanced rectal CA with known IBD

2. Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08
Allegra CJ et al.
J Clin Oncol 2011; 1(29); 11-16
Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?
Eric Van Cutsem et al.
J Clin Oncol (29); 1-4

3. AVANT: Results from a Randomized, Three-Arm Multinational Phase III Study to Investigate Bevacizumab with Either XELOX or FOLFOX4 vs FOLFOX4 Alone as Adjuvant Treatment for Colon Cancer
De Gramont A et al. Proc GI Cancers Symposium 2011;Abstract 362.

4. Case presented by Dr Moriarty
83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies
2010: Increased bleeding and abdominal pressure
PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes
Biopsy = adenocarcinoma of the rectum
Consultation to discuss tx for locally advanced rectal CA with known IBD