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Sex and Body Mass Index but Not CXCL12 801 G/A Polymorphism Determine the Efficacy of Hematopoietic Cell Mobilization: A Study in Healthy Volunteer Donors 

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Presentation on theme: "Sex and Body Mass Index but Not CXCL12 801 G/A Polymorphism Determine the Efficacy of Hematopoietic Cell Mobilization: A Study in Healthy Volunteer Donors "— Presentation transcript:

1 Sex and Body Mass Index but Not CXCL12 801 G/A Polymorphism Determine the Efficacy of Hematopoietic Cell Mobilization: A Study in Healthy Volunteer Donors  Juliane Lenk, Martin Bornhauser, Michael Kramer, Kristina Hölig, Kirsten Poppe-Thiede, Helmuth Schmidt, Markus Wiesneth, Kerstin Schaefer-Eckart, Peter Schlenke, Michael Punzel, Sonja Martin, Frank Kroschinsky, Alexander H. Schmidt, Gerhard Ehninger, Christian Thiede  Biology of Blood and Marrow Transplantation  Volume 19, Issue 10, Pages (October 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 CD34 + cell counts/μL peripheral blood on day 5 of G-CSF treatment in correlation to sex (A) and BMI (B), suggesting male donors with high BMI obtain higher cell doses compared with female, lightweight donors. Association of CD34 + cells/μL peripheral blood with sex and BMI was verified in multivariate analysis. (C) Lack of influence of the CXCL12 genotype on the CD34 + cell count/μL peripheral blood on day 5 of G-CSF treatment. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions


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