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Chapter 3 The Cellular Level of Organization
Lecture slides prepared by Curtis DeFriez, Weber State University
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The Cell A cell is the basic unit of all living things.
Prokaryotic cells are simple cells that are Pro (“before”) karyon (“nucleus”) – they have no nucleus. Most are unicellular bacteria. Eukaryotic cells are complex cells with a nucleus and subcellular structures (organelles). All fungi, plants, and animals are eukaryotes.
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A Generalized Cell All eukaryotic cells are composed of three main parts: Plasma membrane or “plasmalemma” Cytoplasm - a gelatin-like substance, plus structural fibers and organelles (but not the nucleus) Nucleus - contains the genetic library of the cell
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A Generalized Cell The plasma membrane forms the cell’s outer boundary and separates the cell’s internal environment from the outside environment. It is a selectively permeable barrier, allowing the passage of some things and not others. It plays a role in cellular communication.
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A Generalized Cell The cytoplasm contains all the cellular contents between the plasma membrane and the nucleus. The cytosol is the fluid portion (mostly water). Organelles are subcellular structures embedded in the cytosol, having characteristic shapes and specific functions.
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A Generalized Cell The nucleus is a large organelle that contains DNA in molecules called chromosomes. Each chromosome consists of a single molecule of DNA and associated packaging proteins. A chromosome contains thousands of hereditary units called genes.
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A Generalized Cell Fig. 3.1 shows a generalized body cell labeled with the plasma membrane, cytoplasm (and organelles) and nucleus.
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The Plasma Membrane The plasma membrane is much more than just a “fence” – it is a flexible yet sturdy, “intelligent” semipermeable regulator that: Covers and protects the cell Controls what goes in and comes out Links to other cells Flies certain “flags” to tell other cells “who” it is
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The Plasma Membrane The Fluid Mosaic Model describes the arrangement of molecules within the membrane: They resemble a sea of phospholipids with protein “icebergs” floating in it. The lipids act as a barrier to certain polar substances. The proteins act as “gatekeepers”, allowing passage of specific molecules and ions.
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The Plasma Membrane Interactions Animation
Membrane Functions You must be connected to the internet to run this animation.
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The Plasma Membrane The structure of the membrane
Phospholipids form a lipid bilayer - cholesterol and glycolipids (sugar-lipids) also contribute. Integral proteins - extend into or through the bilayer. Transmembrane proteins (most integral proteins) span the entire lipid bilayer. Peripheral proteins attach to the inner or outer surface but do not extend through the membrane.
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The Plasma Membrane
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The Plasma Membrane Glycoproteins are membrane proteins with a carbohydrate group attached that protrude into the extracellular fluid. The Glycocalyx is the entire “sugary coating” surrounding the membrane (made up of the carbohydrate portions of the glycolipids and glycoproteins).
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The Plasma Membrane The Functions of the membrane
Some integral proteins are ion channels. Transporters - selectively move substances through the membrane. Receptors - for cellular recognition; a ligand is a molecule that binds with a receptor. Enzymes - catalyze chemical reactions Others act as cell-identity markers.
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