1. Endocrine and Metabolic Manifestations of Invasive Fungal Infections and Systemic Antifungal Treatment 
Michail S. Lionakis, MD, ScD, George Samonis, MD, Dimitrios P. Kontoyiannis, MD, MS, ScD 
Mayo Clinic Proceedings 
Volume 83, Issue 9, Pages (September 2008)
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2. FIGURE
The main pathways of steroidogenesis in the adrenal glands and inhibitory effects of ketoconazole. The principal enzymes inhibited by ketoconazole are shown in yellow, and the main steroid products whose synthesis is decreased by ketoconazole are shown in red. H = hydrogen; HSD = hydroxysteroid dehydrogenase; O = oxygen; OH = hydroxylase; OHD = hydroxy dehydrogenase; SCC = cholesterol side-chain cleavage.
Adapted from Hardman JG, Limbird LE, Gilman AG. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 11th ed. New York, NY: McGraw-Hill, 2006, with permission of McGraw-Hill.
Mayo Clinic Proceedings  , DOI: ( / )
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