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New Data on the Safety of SGLT2 Inhibitors

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Presentation on theme: "New Data on the Safety of SGLT2 Inhibitors"— Presentation transcript:

1 New Data on the Safety of SGLT2 Inhibitors

2

3 Program Goals

4 The Newest Antihyperglycemic Class SGLT2 Inhibitors

5 DKA

6 SGLT2 Inhibitor-Induced Euglycemic DKA

7 Euglycemic DKA: Case Studies

8 DKA: Canagliflozin Clinical Program

9 EMPA-REG OUTCOME TRIAL DKA

10 SGLT2 Inhibitor-Induced DKA A Diagnostic Challenge

11 Euglycemic DKA Predictable and Detectable

12 DKA Prevention

13 Bone Fractures A Possible Risk With SGLT2 Inhibitors

14 Bone Fractures with SGLT2 Inhibitors Possible Mechanism?

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16 EMPA-REG OUTCOME TRIAL Bone Fractures

17 Clinical Relevance Use of SGLT2 Inhibitors in Older Individuals

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19 2015 AACE/ACE Expert Recommendations: DKA

20 2015 AACE/ACE Expert Recommendations: DKA (cont)

21 Risk Factors for Recurrent Falls

22 Abbreviations


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