1. Course of Immunology - introduction (2016/2017)
Marta Sobotková

2. Course structure ● Lectures Presence in lectures is obligatory
Lectures are held every Tuesday at 8:00-9:40
Small Lecture Hall
- Three absences are tolerated, more frequent absences must be based on official certificate and will be solved individually

3.
Immune system, overview. Phagocytic cells, complement. Communication between cells of immune systems, adhesion molecules, cytokines.
Špíšek
Antigen processing and presentation, HLA I and II class.
Šedivá
Immunity against infection.
Adkins
Specific (adaptive) immunity T and B lymphocytes.
Palich - Fučíková
Immunodeficiency,vaccination.
Immunity against tumors.
Immunology of transplantation.
Kalina
Autoimmunity. Immunopathology.
Sobotková
Immunopathological reactions,allergy.
Klocperk
Immunotherapy.
Podrazil
Clinical aspects of immune disorders.
Horváth

4. Course structure
● Seminars - The first seminar and presentation of your thesis are compulsory; the time of other seminars is devoted to self-studying, preparation of seminar thesis and consultations with teachers

5. Seminar thesis ● groups of 1-3 students ● structure of thesis:
1000 – 2000 words
form of an essay
briefly & concisely & interestingly
Abstract, text and references (literature) are obligatory, subchapters and discussion are recommended
●Term of submission: until
in the digital form (doc, docx form preffered)
- has to be sent to:

6. Oral presentations November 23, 30 and December 7 time 8.00-9.40
November 24 and December 1 and 8
- each thesis will be presented verbally
- range: 8 minutes
Powerpoint presentation (6-10 slides)

7. Final appraisal ● Presence on lectures ● Seminar thesis:
fulfilled / not fulfilled
+ verbal appraisal (after presentation)
● Verbal examination:
2 out of 50 questions

8. Evaluation of the essay:
1/ Adherence to the length limits
2/ Correct content of the essay, no serious misunderstandings
3/ Satisfactory graphical layout and style of the essay
Other comments:
Evaluation of the verbal presentation:
3/ Satisfactory graphical layout and style of the presentation

9. http://imunologie.lf2.cuni.cz/ ● shedules ● presentations (download
possible)
● recommended literature, links
● contacts

10. Citation
Most of the patients are hemizygous for 22q11.2, some have defects in various loci on chromosome 10, about 10% of cases are familial (2, 3).
Literature / References:
2. DRISCOLL DA, SALVIN J, SELLINGER B, et al. Prevalence of 22q11 microdeletions in DiGeorge and velocardiofacial syndromes: implications for genetic counselling and prenatal diagnosis. J Med Genet 1993: 30:
3. SEDIVA A, BARTUNKOVA J, ZACHOVA R, et al. Early development of immunity in diGeorge syndrome. Med Sci Monit 2005: 11:

11. Sources
Bibliographic databases
Clinical sources online

12. Pubmed –

13. Medscape - www.emedicine.com

14. Up-to-date – www.uptodate.com

15. Orphanet – www.orpha.net

16. Good luck with Your essays and presentations !
Marta Sobotková