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Transport across Plasma Membranes
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Transport through plasma membranes
Passive transport modalities -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion. -Facilitated diffusion: by carriers Differences in diffusion Kinetics between the previous modalities Equivalent Concentration of particles.
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Transport through plasma membranes
Passive transport modalities -Osmosis: concept of osmotic pressure (Van’t Hoff’s law), Oncotic (Colloid-osmotic) pressure.Osmolarity, osmolality Hydrostatic pressure
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Transport through plasma membranes
Active transport modalities - Primary active transport (ATP-ase carriers or Pumps) (functions of pumps: Na+/K+ pump, Ca++ pump, H+ pump, H+/K+ pump). - Secondary active transport (Na+ dependent carriers) examples
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Transport through plasma membranes
Active transport modalities - Vesicular transport: endocytosis, phagocytosis, transcytosis, pinocytosis and exocytosis and its control in secretory cells.-
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Active Transport Mechanisms
Primary active transport Secondary active transport Vesicular transport
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Types of Pumps Na+/K+ pump H+ pump H+/K+ pump Ca++ pump
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Phosphorylation & dephosphorylation
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Types of Pumps Na+/K+ pump H+ pump H+/K+ pump Ca++ pump
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The importance of pumps for cell functions
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Secondary Active Transport
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Secondary Active Transport
Co-transport Counter transport
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Vesicular Transport
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Formation of vesicles at ER
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Endocytosis
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Phagocytosis
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Receptor mediated endcytosis
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Exocytosis
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Transcytosis
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Control of Transport
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Receptors & Enzymes
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Receptors & Channels
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Receptors & G proteins
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Control of Transport and activity of Enzymes
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Transport is Controlled by
Activation of receptors - Changing activity of enzymes
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Control of Exocytosis
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