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Transport across Plasma Membranes

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Presentation on theme: "Transport across Plasma Membranes"— Presentation transcript:

1 Transport across Plasma Membranes

2 Transport through plasma membranes
Passive transport modalities -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion. -Facilitated diffusion: by carriers Differences in diffusion Kinetics between the previous modalities Equivalent Concentration of particles.

3 Transport through plasma membranes
Passive transport modalities -Osmosis: concept of osmotic pressure (Van’t Hoff’s law), Oncotic (Colloid-osmotic) pressure.Osmolarity, osmolality Hydrostatic pressure

4 Transport through plasma membranes
Active transport modalities - Primary active transport (ATP-ase carriers or Pumps) (functions of pumps: Na+/K+ pump, Ca++ pump, H+ pump, H+/K+ pump). - Secondary active transport (Na+ dependent carriers) examples

5 Transport through plasma membranes
Active transport modalities - Vesicular transport: endocytosis, phagocytosis, transcytosis, pinocytosis and exocytosis and its control in secretory cells.-

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7 Active Transport Mechanisms
Primary active transport Secondary active transport Vesicular transport

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9 Types of Pumps Na+/K+ pump H+ pump H+/K+ pump Ca++ pump

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12 Phosphorylation & dephosphorylation

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14 Types of Pumps Na+/K+ pump H+ pump H+/K+ pump Ca++ pump

15 The importance of pumps for cell functions

16 Secondary Active Transport

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18 Secondary Active Transport
Co-transport Counter transport

19 Vesicular Transport

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21 Formation of vesicles at ER

22 Endocytosis

23 Phagocytosis

24 Receptor mediated endcytosis

25 Exocytosis

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27 Transcytosis

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29 Control of Transport

30 Receptors & Enzymes

31 Receptors & Channels

32 Receptors & G proteins

33 Control of Transport and activity of Enzymes

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37 Transport is Controlled by
Activation of receptors - Changing activity of enzymes

38 Control of Exocytosis


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