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Published byViolette Goulet Modified over 6 years ago
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Lsh does not regulate global histone methylation levels.
Lsh does not regulate global histone methylation levels. (A) Loss of Lsh does not alter H3‐K9me, H3‐K4me or Hp1 protein levels. Western analysis of nuclear extracts derived from four Lsh‐deficient embryos (gestation day 14) and their wild‐type littermates. (B) Titration of nuclear extracts of one wild‐type and one Lsh‐deficient embryo. (C) Loss of Lsh does not alter Hp1 binding to chromatin. Lsh‐deficient and Lsh wild‐type MEFs are compared for resistance to Triton X‐100 washes followed by western analysis to detect HP1 or PCNA and Vimentin as control. Qingsheng Yan et al. EMBO J. 2003;22: © as stated in the article, figure or figure legend
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