1. Metabolic Energy

2. Metabolic Energy

3. Metabolic Energy

4. Metabolic Energy

5. ∆G = ∆G°’ + RTln([B]b/[A]a) For aA + cC ⇄ bB + dD
Metabolic Energy
For aA ⇄ bB
∆G = ∆G°’ + RTln([B]b/[A]a)
For aA + cC ⇄ bB + dD
∆G = ∆G°’ + RTln{([B]b[D]d)/([A]a[C]c)}
∆G = ∆G°’ + RTln({Products}/{Reactants})

6. if ΔG is negative, A->B is favored
Metabolic Energy
For A <=> B
if ΔG is negative, A->B is favored
if ΔG is positive, B-> A is favored
if ΔG is 0, B-> A and A-> B are equally favored
At ΔG = 0, the system is at equilibrium

7. Creatine + ATP <=> Creatine Phosphate + ADP
Metabolic Energy
Muscle Energy
Creatine Kinase
Creatine + ATP <=> Creatine Phosphate + ADP
ΔG0' = +12 kJ/mol

8. Metabolic Energy

9. Metabolic Energy

10. Metabolic Energy

11. Metabolic Energy
Nicotinamide
Dinucleotide
Adenine

12. Metabolic Energy Coupled Reactions
Glucose + Pi <=> Glucose-6-Phosphate ΔG°’ = +14 kJ/mol
Glucose + ATP <=> Glucose-6-Phosphate ΔG°’ = kJ/mol

13. Metabolic Pathways

14. Metabolic Pathways

15. Metabolic Pathways

16. Metabolic Pathways

17. ΔG°’ Values of Hydrolysis (kJ/mol)
Metabolic Pathways
ΔG°’ Values of Hydrolysis (kJ/mol)
PEP = -61.9
1,3 BPG = -49.4
Creatine Phosphate = -43.1
ATP to ADP = -30.5
G1P = -20.9
Pyrophosphate = -19.3