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Chee Khoon Lee, PhD, Johnathan Man, M. B. B. S

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Presentation on theme: "Chee Khoon Lee, PhD, Johnathan Man, M. B. B. S"— Presentation transcript:

1 Checkpoint Inhibitors in Metastatic EGFR-Mutated Non–Small Cell Lung Cancer—A Meta-Analysis 
Chee Khoon Lee, PhD, Johnathan Man, M.B.B.S., Sally Lord, MSc, Matthew Links, PhD, Val Gebski, MStat, Tony Mok, MD, James Chih-Hsin Yang, PhD  Journal of Thoracic Oncology  Volume 12, Issue 2, Pages (February 2017) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Flow diagram showing inclusion and exclusion of studies.
Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Forest plot of hazard ratios comparing overall survival in the EGFR gene wild-type and mutated subgroups in patients who received programmed death 1 (PD-1) or programmed death ligand 1 (PD-L1) immune checkpoint inhibitors versus docetaxel. Hazard ratios for each trial are represented by the squares, and the horizontal line crossing the squares represents the 95% confidence interval (CI). The diamonds represent the estimated overall effect based on the meta-analysis fixed effect of the trials. All statistical tests were two sided. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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