1. An Update on Oral Prostanoids: Advancing Care for PAH?

2. Program Goals

5. Prostacyclin Analogues and Prostacyclin Receptor Agonists

6. Therapies Targeting the Prostacyclin Pathway

7. FREEDOM Trials Oral Treprostinil

9. GRIPHON Primary Endpoint

10. Patient Selection for Oral Prostanoid Therapy

11. Can Patients Be Transitioned From Parenteral or Inhaled Prostanoid to an Oral Prostanoid?

12. Treatment Algorithm for PAH

13. Treatment Algorithm for PAH (cont)

14. Treatment Algorithm for PAH (cont)

15. Treatment Options for Less Severely Ill Patients: Functional Class II or III

16. The Ambrisentan and Tadalafil in Patients With PAH (AMBITION) Trial

17. The Rationale for Combination Therapy

18. Side Effects of Oral Prostanoids

19. GRIPHON Titration and Dosing

21. Dose Titration

22. Summary

23. Abbreviations