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Etiology and Therapeutic Approach to Elevated Lactate Levels

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Presentation on theme: "Etiology and Therapeutic Approach to Elevated Lactate Levels"— Presentation transcript:

1 Etiology and Therapeutic Approach to Elevated Lactate Levels
Lars W. Andersen, MD, Julie Mackenhauer, MD, Jonathan C. Roberts, MD, Katherine M. Berg, MD, Michael N. Cocchi, MD, Michael W. Donnino, MD  Mayo Clinic Proceedings  Volume 88, Issue 10, Pages (October 2013) DOI: /j.mayocp Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Aerobic and anaerobic metabolism. ATP = adenosine triphosphate; CoA = coenzyme A; PDH = pyruvate dehydrogenase. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Elevated lactate levels (>4 mmol/L) in different diseases and its association with in-hospital mortality.9-11,40 The mortality in post–cardiac arrest shown here is calculated based on data from Cocchi et al40 and not specified in the original article. ED = emergency department. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions


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